Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2675
MIM: 601956
HGNC: 4244
Ensembl: ENSG00000168546
Variants:
dbSNP: 2675
ClinVar: 2675
TCGA: ENSG00000168546
COSMIC: GFRA2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30722993 | 2019 | GDNF family receptor alpha 2 promotes neuroblastoma cell proliferation by interacting with PTEN. | 15 |
| 31392261 | 2019 | Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain. | 11 |
| 30722993 | 2019 | GDNF family receptor alpha 2 promotes neuroblastoma cell proliferation by interacting with PTEN. | 15 |
| 31392261 | 2019 | Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain. | 11 |
| 29414779 | 2018 | Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling. | 17 |
| 29724592 | 2018 | Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. | 65 |
| 29414779 | 2018 | Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling. | 17 |
| 29724592 | 2018 | Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. | 65 |
| 27396331 | 2016 | GFRA2 Identifies Cardiac Progenitors and Mediates Cardiomyocyte Differentiation in a RET-Independent Signaling Pathway. | 15 |
| 27400681 | 2016 | GFRα2 prompts cell growth and chemoresistance through down-regulating tumor suppressor gene PTEN via Mir-17-5p in pancreatic cancer. | 36 |
| 27396331 | 2016 | GFRA2 Identifies Cardiac Progenitors and Mediates Cardiomyocyte Differentiation in a RET-Independent Signaling Pathway. | 15 |
| 27400681 | 2016 | GFRα2 prompts cell growth and chemoresistance through down-regulating tumor suppressor gene PTEN via Mir-17-5p in pancreatic cancer. | 36 |
| 24402129 | 2015 | Expression of the pituitary stem/progenitor marker GFRα2 in human pituitary adenomas and normal pituitary. | 4 |
| 24974787 | 2015 | A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain. | 34 |
| 24402129 | 2015 | Expression of the pituitary stem/progenitor marker GFRα2 in human pituitary adenomas and normal pituitary. | 4 |
Citation
Dessen P
GFRA2 (GDNF family receptor alpha 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-04-01
Online version: http://atlasgeneticsoncology.org/gene/53862/gfra2-(gdnf-family-receptor-alpha-2)
