Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55677
HGNC: 25467
Ensembl: ENSG00000163166
Variants:
dbSNP: 55677
ClinVar: 55677
TCGA: ENSG00000163166
COSMIC: IWS1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000163166 | ENST00000295321 | Q96ST2 |
| ENSG00000163166 | ENST00000409725 | B8ZZB6 |
| ENSG00000163166 | ENST00000412979 | H7C0U1 |
| ENSG00000163166 | ENST00000637187 | A0A1B0GW95 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34822292 | 2021 | A ubiquitous disordered protein interaction module orchestrates transcription elongation. | 19 |
| 34822292 | 2021 | A ubiquitous disordered protein interaction module orchestrates transcription elongation. | 19 |
| 25590759 | 2015 | The integrase cofactor LEDGF/p75 associates with Iws1 and Spt6 for postintegration silencing of HIV-1 gene expression in latently infected cells. | 27 |
| 26245978 | 2015 | Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif. | 35 |
| 25590759 | 2015 | The integrase cofactor LEDGF/p75 associates with Iws1 and Spt6 for postintegration silencing of HIV-1 gene expression in latently infected cells. | 27 |
| 26245978 | 2015 | Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif. | 35 |
| 24462114 | 2014 | Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer. | 61 |
| 24462114 | 2014 | Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer. | 61 |
| 19141475 | 2008 | The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation. | 133 |
| 19141475 | 2008 | The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation. | 133 |
| 17184735 | 2007 | A putative transcriptional elongation factor hIws1 is essential for mammalian cell proliferation. | 18 |
| 17234882 | 2007 | The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export. | 136 |
| 17184735 | 2007 | A putative transcriptional elongation factor hIws1 is essential for mammalian cell proliferation. | 18 |
| 17234882 | 2007 | The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export. | 136 |
Citation
Dessen P
IWS1 (interacts with SUPT6H, CTD assembly factor 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-05-01
Online version: http://atlasgeneticsoncology.org/gene/53884/iws1-(interacts-with-supt6h-ctd-assembly-factor-1)
