RAB29 (RAB29, member RAS oncogene family)

2014-05-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
RAB7L,RAB7L1
FUSION GENES

Other Information

Locus ID:

NCBI: 8934
MIM: 603949
HGNC: 9789
Ensembl: ENSG00000117280

Variants:

dbSNP: 8934
ClinVar: 8934
TCGA: ENSG00000117280
COSMIC: RAB29

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117280ENST00000235932O14966
ENSG00000117280ENST00000235932Q6FGU7
ENSG00000117280ENST00000367139O14966
ENSG00000117280ENST00000367139Q6FGU7
ENSG00000117280ENST00000414729O14966
ENSG00000117280ENST00000414729Q6FGU7
ENSG00000117280ENST00000437324O14966
ENSG00000117280ENST00000446390O14966
ENSG00000117280ENST00000528078E9PL56

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
361165512022The atypical Rab GTPase associated with Parkinson's disease, Rab29, is localized to membranes.0
361165512022The atypical Rab GTPase associated with Parkinson's disease, Rab29, is localized to membranes.0
339415582021Expression of RAB7L1 in Patients with Pituitary Adenomas.0
339415582021Expression of RAB7L1 in Patients with Pituitary Adenomas.0
318185092020Association of RIT2 and RAB7L1 with Parkinson's disease: a case-control study in a Taiwanese cohort and a meta-analysis in Asian populations.3
327090662020Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations.16
318185092020Association of RIT2 and RAB7L1 with Parkinson's disease: a case-control study in a Taiwanese cohort and a meta-analysis in Asian populations.3
327090662020Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations.16
316241372019Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases.48
316241372019Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases.48
291775062018LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network.128
292233922018Parkinson's disease-associated mutant LRRK2 phosphorylates Rab7L1 and modifies trans-Golgi morphology.51
300378482018Mycobacterial PknG Targets the Rab7l1 Signaling Pathway To Inhibit Phagosome-Lysosome Fusion.32
291775062018LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network.128
292233922018Parkinson's disease-associated mutant LRRK2 phosphorylates Rab7L1 and modifies trans-Golgi morphology.51

Citation

Dessen P

RAB29 (RAB29, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2014-05-01

Online version: http://atlasgeneticsoncology.org/gene/53890/rab29-(rab29-member-ras-oncogene-family)