Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 85464
MIM: 606779
HGNC: 30580
Ensembl: ENSG00000141298
Variants:
dbSNP: 85464
ClinVar: 85464
TCGA: ENSG00000141298
COSMIC: SSH2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Axon guidance | KEGG | ko04360 |
| Regulation of actin cytoskeleton | KEGG | ko04810 |
| Axon guidance | KEGG | hsa04360 |
| Regulation of actin cytoskeleton | KEGG | hsa04810 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30154244 | 2018 | Allosteric modulation of the catalytic VYD loop in Slingshot by its N-terminal domain underlies both Slingshot auto-inhibition and activation. | 0 |
| 30154244 | 2018 | Allosteric modulation of the catalytic VYD loop in Slingshot by its N-terminal domain underlies both Slingshot auto-inhibition and activation. | 0 |
| 25568344 | 2015 | GPCR-mediated PLCβγ/PKCβ/PKD signaling pathway regulates the cofilin phosphatase slingshot 2 in neutrophil chemotaxis. | 31 |
| 25568344 | 2015 | GPCR-mediated PLCβγ/PKCβ/PKD signaling pathway regulates the cofilin phosphatase slingshot 2 in neutrophil chemotaxis. | 31 |
| 23416984 | 2014 | Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dubé tumour suppressor gene (FLCN). | 6 |
| 23416984 | 2014 | Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dubé tumour suppressor gene (FLCN). | 6 |
| 20477815 | 2010 | Mutational analysis of mononucleotide repeats in dual specificity tyrosine phosphatase genes in gastric and colon carcinomas with microsatellite instability. | 5 |
| 20477815 | 2010 | Mutational analysis of mononucleotide repeats in dual specificity tyrosine phosphatase genes in gastric and colon carcinomas with microsatellite instability. | 5 |
| 17848544 | 2007 | The slingshot family of phosphatases mediates Rac1 regulation of cofilin phosphorylation, laminin-332 organization, and motility behavior of keratinocytes. | 44 |
| 17848544 | 2007 | The slingshot family of phosphatases mediates Rac1 regulation of cofilin phosphorylation, laminin-332 organization, and motility behavior of keratinocytes. | 44 |
Citation
Dessen P
SSH2 (slingshot protein phosphatase 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-05-01
Online version: http://atlasgeneticsoncology.org/gene/53893/ssh2-(slingshot-protein-phosphatase-2)
