Identity
HGNC
LOCATION
22q12.1
LOCUSID
ALIAS
BK747E2.3,RNF203
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84133
MIM: 612062
HGNC: 18126
Ensembl: ENSG00000183579
Variants:
dbSNP: 84133
ClinVar: 84133
TCGA: ENSG00000183579
COSMIC: ZNRF3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000183579 | ENST00000402174 | Q9ULT6 |
| ENSG00000183579 | ENST00000406323 | Q9ULT6 |
| ENSG00000183579 | ENST00000544604 | Q9ULT6 |
| ENSG00000183579 | ENST00000544604 | A0A024R1J1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37878959 | 2024 | Single-Exon Deletions of ZNRF3 Exon 2 Cause Congenital Adrenal Hypoplasia. | 0 |
| 38056465 | 2024 | Potent and selective binders of the E3 ubiquitin ligase ZNRF3 stimulate Wnt signaling and intestinal organoid growth. | 1 |
| 38457275 | 2024 | Comprehensive analysis of zinc and ring finger 3 in prognostic value and pan-cancer immunity. | 0 |
| 37878959 | 2024 | Single-Exon Deletions of ZNRF3 Exon 2 Cause Congenital Adrenal Hypoplasia. | 0 |
| 38056465 | 2024 | Potent and selective binders of the E3 ubiquitin ligase ZNRF3 stimulate Wnt signaling and intestinal organoid growth. | 1 |
| 38457275 | 2024 | Comprehensive analysis of zinc and ring finger 3 in prognostic value and pan-cancer immunity. | 0 |
| 36631813 | 2023 | Additional evidence for the role of chromosomal imbalances and SOX8, ZNRF3 and HHAT gene variants in early human testis development. | 2 |
| 36631813 | 2023 | Additional evidence for the role of chromosomal imbalances and SOX8, ZNRF3 and HHAT gene variants in early human testis development. | 2 |
| 35039505 | 2022 | RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state. | 12 |
| 35039505 | 2022 | RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state. | 12 |
| 33367931 | 2021 | MicroRNA‑301a/ZNRF3/wnt/β‑catenin signal regulatory crosstalk mediates glioma progression. | 5 |
| 33513905 | 2021 | Low Protein Expression of both ATRX and ZNRF3 as Novel Negative Prognostic Markers of Adult Adrenocortical Carcinoma. | 7 |
| 34273374 | 2021 | RSPO2 silence inhibits tumorigenesis of nasopharyngeal carcinoma by ZNRF3/Hedgehog-Gli1 signal pathway. | 3 |
| 34590584 | 2021 | A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling. | 3 |
| 34657141 | 2021 | A positive feedback loop of lncRNA-RMRP/ZNRF3 axis and Wnt/β-catenin signaling regulates the progression and temozolomide resistance in glioma. | 17 |
Citation
Dessen P
ZNRF3 (zinc and ring finger 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-05-01
Online version: http://atlasgeneticsoncology.org/gene/53896/znrf3-(zinc-and-ring-finger-3)
