CKAP2 (cytoskeleton associated protein 2)

2014-05-01  

Identity

HGNC
LOCATION
13q14.3
LOCUSID
ALIAS
LB1,TMAP,se20-10
FUSION GENES

Other Information

Locus ID:

NCBI: 26586
MIM: 611569
HGNC: 1990
Ensembl: ENSG00000136108

Variants:

dbSNP: 26586
ClinVar: 26586
TCGA: ENSG00000136108
COSMIC: CKAP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136108ENST00000258607Q8WWK9
ENSG00000136108ENST00000378034Q8WWK9
ENSG00000136108ENST00000378037Q8WWK9
ENSG00000136108ENST00000468284C9J649
ENSG00000136108ENST00000480747C9J7Y4
ENSG00000136108ENST00000490903Q8WWK9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
358538542022Long non-coding RNA DLEU1 promotes malignancy of breast cancer by acting as an indispensable coactivator for HIF-1α-induced transcription of CKAP2.3
359052132022CKAP2 overexpression correlates with worse overall survival in patients with lung adenocarcinoma.0
358538542022Long non-coding RNA DLEU1 promotes malignancy of breast cancer by acting as an indispensable coactivator for HIF-1α-induced transcription of CKAP2.3
359052132022CKAP2 overexpression correlates with worse overall survival in patients with lung adenocarcinoma.0
342166442021Cytoskeleton-associated protein 2 (CKAP2) is regulated by vascular endothelial growth factor and p53 in retinal capillary endothelial cells under high-glucose conditions.1
345960062021LncRNA DARS-AS1 aggravates the growth and metastasis of hepatocellular carcinoma via regulating the miR-3200-5p-Cytoskeleton associated protein 2 (CKAP2) axis.18
342166442021Cytoskeleton-associated protein 2 (CKAP2) is regulated by vascular endothelial growth factor and p53 in retinal capillary endothelial cells under high-glucose conditions.1
345960062021LncRNA DARS-AS1 aggravates the growth and metastasis of hepatocellular carcinoma via regulating the miR-3200-5p-Cytoskeleton associated protein 2 (CKAP2) axis.18
300669462018CKAP2 expression is associated with glioma tumor growth and acts as a prognostic factor in high‑grade glioma.18
301192122018Silencing of cytoskeleton-associated protein 2 represses cell proliferation and induces cell cycle arrest and cell apoptosis in osteosarcoma cells.12
300669462018CKAP2 expression is associated with glioma tumor growth and acts as a prognostic factor in high‑grade glioma.18
301192122018Silencing of cytoskeleton-associated protein 2 represses cell proliferation and induces cell cycle arrest and cell apoptosis in osteosarcoma cells.12
285228602017Involvement of FAK-ERK2 signaling pathway in CKAP2-induced proliferation and motility in cervical carcinoma cell lines.15
289335612017CKAP2 Promotes Ovarian Cancer Proliferation and Tumorigenesis Through the FAK-ERK Pathway.13
285228602017Involvement of FAK-ERK2 signaling pathway in CKAP2-induced proliferation and motility in cervical carcinoma cell lines.15

Citation

Dessen P

CKAP2 (cytoskeleton associated protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-05-01

Online version: http://atlasgeneticsoncology.org/gene/53897/ckap2-(cytoskeleton-associated-protein-2)