Identity
HGNC
LOCATION
6p12.3
LOCUSID
ALIAS
GPR116,KPG_001
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 221395
HGNC: 19030
Ensembl: ENSG00000069122
Variants:
dbSNP: 221395
ClinVar: 221395
TCGA: ENSG00000069122
COSMIC: ADGRF5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000069122 | ENST00000265417 | Q8IZF2 |
| ENSG00000069122 | ENST00000283296 | Q8IZF2 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Surfactant metabolism | REACTOME | R-HSA-5683826 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38937435 | 2024 | The adhesion-GPCR ADGRF5 fuels breast cancer progression by suppressing the MMP8-mediated antitumorigenic effects. | 0 |
| 39001944 | 2024 | GPR116 alleviates acetaminophen-induced liver injury in mice by inhibiting endoplasmic reticulum stress. | 0 |
| 38937435 | 2024 | The adhesion-GPCR ADGRF5 fuels breast cancer progression by suppressing the MMP8-mediated antitumorigenic effects. | 0 |
| 39001944 | 2024 | GPR116 alleviates acetaminophen-induced liver injury in mice by inhibiting endoplasmic reticulum stress. | 0 |
| 36878303 | 2023 | The clinical relevance of the adhesion G protein-coupled receptor F5 for human diseases and cancers. | 2 |
| 36878303 | 2023 | The clinical relevance of the adhesion G protein-coupled receptor F5 for human diseases and cancers. | 2 |
| 36497132 | 2022 | The Expression Pattern of Adhesion G Protein-Coupled Receptor F5 Is Related to Cell Adhesion and Metastatic Pathways in Colorectal Cancer-Comprehensive Study Based on In Silico Analysis. | 4 |
| 36497132 | 2022 | The Expression Pattern of Adhesion G Protein-Coupled Receptor F5 Is Related to Cell Adhesion and Metastatic Pathways in Colorectal Cancer-Comprehensive Study Based on In Silico Analysis. | 4 |
| 34016966 | 2021 | Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue. | 17 |
| 34016966 | 2021 | Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue. | 17 |
| 32047233 | 2020 | Recurrent novel THBS1-ADGRF5 gene fusion in a new tumor subtype "Acral FibroChondroMyxoid Tumors". | 3 |
| 33004624 | 2020 | Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion. | 19 |
| 32047233 | 2020 | Recurrent novel THBS1-ADGRF5 gene fusion in a new tumor subtype "Acral FibroChondroMyxoid Tumors". | 3 |
| 33004624 | 2020 | Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion. | 19 |
| 31364112 | 2019 | MiR-511-5p functions as a tumor suppressor and a predictive of prognosis in colorectal cancer by directly targeting GPR116. | 13 |
Citation
Dessen P
ADGRF5 (adhesion G protein-coupled receptor F5)
Atlas Genet Cytogenet Oncol Haematol. 2014-05-01
Online version: http://atlasgeneticsoncology.org/gene/53899/adgrf5-(adhesion-g-protein-coupled-receptor-f5)
