Identity
HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
CGI-104,HSPC172,NEDESBA,PTD009,SBDN,SYNBINDIN,TRS23
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51399
MIM: 610971
HGNC: 19943
Ensembl: ENSG00000196655
Variants:
dbSNP: 51399
ClinVar: 51399
TCGA: ENSG00000196655
COSMIC: TRAPPC4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32901138 | 2021 | A relatively common homozygous TRAPPC4 splicing variant is associated with an early-infantile neurodegenerative syndrome. | 6 |
| 34518538 | 2021 | TRAPPC4 regulates the intracellular trafficking of PD-L1 and antitumor immunity. | 23 |
| 32901138 | 2021 | A relatively common homozygous TRAPPC4 splicing variant is associated with an early-infantile neurodegenerative syndrome. | 6 |
| 34518538 | 2021 | TRAPPC4 regulates the intracellular trafficking of PD-L1 and antitumor immunity. | 23 |
| 31794024 | 2020 | Deficiencies in vesicular transport mediated by TRAPPC4 are associated with severe syndromic intellectual disability. | 19 |
| 31794024 | 2020 | Deficiencies in vesicular transport mediated by TRAPPC4 are associated with severe syndromic intellectual disability. | 19 |
| 30561033 | 2019 | Synbindin deficiency inhibits colon carcinogenesis by attenuating Wnt cascade and balancing gut microbiome. | 6 |
| 30561033 | 2019 | Synbindin deficiency inhibits colon carcinogenesis by attenuating Wnt cascade and balancing gut microbiome. | 6 |
| 23625650 | 2014 | The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4. | 7 |
| 23625650 | 2014 | The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4. | 7 |
| 24104608 | 2013 | Synbindin in extracellular signal-regulated protein kinase spatial regulation and gastric cancer aggressiveness. | 18 |
| 24104608 | 2013 | Synbindin in extracellular signal-regulated protein kinase spatial regulation and gastric cancer aggressiveness. | 18 |
| 21826244 | 2011 | TRAPPC4-ERK2 interaction activates ERK1/2, modulates its nuclear localization and regulates proliferation and apoptosis of colorectal cancer cells. | 13 |
| 21826244 | 2011 | TRAPPC4-ERK2 interaction activates ERK1/2, modulates its nuclear localization and regulates proliferation and apoptosis of colorectal cancer cells. | 13 |
| 18466758 | 2009 | Crystal structure of human synbindin reveals two conformations of longin domain. | 5 |
Citation
Dessen P
TRAPPC4 (trafficking protein particle complex subunit 4)
Atlas Genet Cytogenet Oncol Haematol. 2014-05-01
Online version: http://atlasgeneticsoncology.org/gene/53909/trappc4-(trafficking-protein-particle-complex-subunit-4)
