VEZT (vezatin, adherens junctions transmembrane protein)

2014-05-01  

Identity

HGNC
VEZT
LOCATION
12q22
LOCUSID
55591
ALIAS
VEZATIN
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55591
HGNC: 18258
Ensembl: ENSG00000028203

Variants:

dbSNP: 55591
ClinVar: 55591
TCGA: ENSG00000028203
COSMIC: VEZT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000028203ENST00000261219F2Z3A6
ENSG00000028203ENST00000397792F8W8C2
ENSG00000028203ENST00000436874Q9HBM0
ENSG00000028203ENST00000546445F8W0S0
ENSG00000028203ENST00000546557Q9HBM0
ENSG00000028203ENST00000547484Q9HBM0
ENSG00000028203ENST00000547611F8VUG0
ENSG00000028203ENST00000547997Q9HBM0
ENSG00000028203ENST00000548245F8W088
ENSG00000028203ENST00000548371F8VUG0
ENSG00000028203ENST00000548455Q9HBM0
ENSG00000028203ENST00000548822F8VUB7
ENSG00000028203ENST00000548838F8VUG0
ENSG00000028203ENST00000549002F8VVS3
ENSG00000028203ENST00000549624Q9HBM0
ENSG00000028203ENST00000550803Q9HBM0
ENSG00000028203ENST00000551039F8VRY3
ENSG00000028203ENST00000551311F8VPN9
ENSG00000028203ENST00000551472F8VXA0
ENSG00000028203ENST00000551994F8VS43
ENSG00000028203ENST00000552660Q9HBM0
ENSG00000028203ENST00000552821F8W048

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
346423202021Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.5
346423202021Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.5
278562442017Up-regulation of VEZT by small activating RNA inhibits the proliferation, invasion and migration of gastric cancer cells.5
289014532017The role of gene polymorphisms in endometriosis.27
278562442017Up-regulation of VEZT by small activating RNA inhibits the proliferation, invasion and migration of gastric cancer cells.5
289014532017The role of gene polymorphisms in endometriosis.27
256785722015Replication and meta-analysis of previous genome-wide association studies confirm vezatin as the locus with the strongest evidence for association with endometriosis.9
257924702015VEZT as a novel independent prognostic factor in gastric cancer.4
256785722015Replication and meta-analysis of previous genome-wide association studies confirm vezatin as the locus with the strongest evidence for association with endometriosis.9
257924702015VEZT as a novel independent prognostic factor in gastric cancer.4
240693102013VEZT, a novel putative tumor suppressor, suppresses the growth and tumorigenicity of gastric cancer.19
240693102013VEZT, a novel putative tumor suppressor, suppresses the growth and tumorigenicity of gastric cancer.19
211561612011Down-regulation of VEZT gene expression in human gastric cancer involves promoter methylation and miR-43c.21
211561612011Down-regulation of VEZT gene expression in human gastric cancer involves promoter methylation and miR-43c.21
161990272005Vezatin, a protein associated to adherens junctions, is required for mouse blastocyst morphogenesis.10

Citation

Dessen P

VEZT (vezatin, adherens junctions transmembrane protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-05-01

Online version: http://atlasgeneticsoncology.org/gene/53910/vezt-(vezatin-adherens-junctions-transmembrane-protein)