TANC2 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2)
2014-05-01 AffiliationIdentity
HGNC
LOCATION
17q23.2
LOCUSID
ALIAS
IDDALDS,ROLSA,rols
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26115
MIM: 615047
HGNC: 30212
Ensembl: ENSG00000170921
Variants:
dbSNP: 26115
ClinVar: 26115
TCGA: ENSG00000170921
COSMIC: TANC2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10407 | calcium channel blockers | Chemical | ClinicalAnnotation | associated | PD | 24192120 | |
| PA444552 | Hypertension | Disease | ClinicalAnnotation | associated | PD | 24192120 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36326272 | 2022 | HPV-18E6 Inhibits Interactions between TANC2 and SNX27 in a PBM-Dependent Manner and Promotes Increased Cell Proliferation. | 2 |
| 36326272 | 2022 | HPV-18E6 Inhibits Interactions between TANC2 and SNX27 in a PBM-Dependent Manner and Promotes Increased Cell Proliferation. | 2 |
| 33976205 | 2021 | Tanc2-mediated mTOR inhibition balances mTORC1/2 signaling in the developing mouse brain and human neurons. | 9 |
| 33976205 | 2021 | Tanc2-mediated mTOR inhibition balances mTORC1/2 signaling in the developing mouse brain and human neurons. | 9 |
| 31616000 | 2019 | Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders. | 23 |
| 31616000 | 2019 | Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders. | 23 |
| 24148822 | 2014 | A siRNA screen identifies RAD21, EIF3H, CHRAC1 and TANC2 as driver genes within the 8q23, 8q24.3 and 17q23 amplicons in breast cancer with effects on cell growth, survival and transformation. | 27 |
| 24148822 | 2014 | A siRNA screen identifies RAD21, EIF3H, CHRAC1 and TANC2 as driver genes within the 8q23, 8q24.3 and 17q23 amplicons in breast cancer with effects on cell growth, survival and transformation. | 27 |
| 22360420 | 2012 | Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. | 24 |
| 22360420 | 2012 | Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. | 24 |
Citation
Dessen P
TANC2 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-05-01
Online version: http://atlasgeneticsoncology.org/gene/53914/tanc2-(tetratricopeptide-repeat-ankyrin-repeat-and-coiled-coil-containing-2)
