APOL2 (apolipoprotein L2)

2014-01-01  

Identity

HGNC
LOCATION
22q12.3
LOCUSID
ALIAS
APOL-II,APOL3
FUSION GENES

Other Information

Locus ID:

NCBI: 23780
MIM: 607252
HGNC: 619
Ensembl: ENSG00000128335

Variants:

dbSNP: 23780
ClinVar: 23780
TCGA: ENSG00000128335
COSMIC: APOL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128335ENST00000249066Q9BQE5
ENSG00000128335ENST00000249066A0A024R1M8
ENSG00000128335ENST00000358502Q9BQE5
ENSG00000128335ENST00000358502A0A024R1M8
ENSG00000128335ENST00000451256J3KQL8
ENSG00000128335ENST00000454728B0QYK8
ENSG00000128335ENST00000529194E9PM95

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
343160152021Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.7
343160152021Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.7
314660812020Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2.39
314660812020Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2.39
249010462014Apolipoprotein L2 contains a BH3-like domain but it does not behave as a BH3-only protein.20
249010462014Apolipoprotein L2 contains a BH3-like domain but it does not behave as a BH3-only protein.20
206657052011A novel anti-apoptotic role for apolipoprotein L2 in IFN-γ-induced cytotoxicity in human bronchial epithelial cells.14
206657052011A novel anti-apoptotic role for apolipoprotein L2 in IFN-γ-induced cytotoxicity in human bronchial epithelial cells.14
206026152010Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?3
206026152010Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?3
186322552008Association of SNPs and haplotypes in APOL1, 2 and 4 with schizophrenia.14
186322552008Association of SNPs and haplotypes in APOL1, 2 and 4 with schizophrenia.14
186322552008Association of SNPs and haplotypes in APOL1, 2 and 4 with schizophrenia.14
186322552008Association of SNPs and haplotypes in APOL1, 2 and 4 with schizophrenia.14
159496552005Investigation of the apolipoprotein-L (APOL) gene family and schizophrenia using a novel DNA pooling strategy for public database SNPs.5

Citation

Dessen P

APOL2 (apolipoprotein L2)

Atlas Genet Cytogenet Oncol Haematol. 2014-01-01

Online version: http://atlasgeneticsoncology.org/gene/53919/apol2-(apolipoprotein-l2)