Identity
HGNC
LOCATION
14q31.3
LOCUSID
ALIAS
K2p10.1,PPP1R97,TREK-2,TREK2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54207
MIM: 605873
HGNC: 6273
Ensembl: ENSG00000100433
Variants:
dbSNP: 54207
ClinVar: 54207
TCGA: ENSG00000100433
COSMIC: KCNK10
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000100433 | ENST00000312350 | P57789 |
| ENSG00000100433 | ENST00000319231 | P57789 |
| ENSG00000100433 | ENST00000340700 | P57789 |
| ENSG00000100433 | ENST00000556282 | G3V5Y5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37296621 | 2023 | β-COP Suppresses the Surface Expression of the TREK2. | 1 |
| 37296621 | 2023 | β-COP Suppresses the Surface Expression of the TREK2. | 1 |
| 34618865 | 2021 | Effects of ionic strength on gating and permeation of TREK-2 K2P channels. | 0 |
| 34618865 | 2021 | Effects of ionic strength on gating and permeation of TREK-2 K2P channels. | 0 |
| 28676394 | 2017 | The glycine hinge of transmembrane segment 2 modulates the subcellular localization and gating properties in TREK channels. | 4 |
| 28676394 | 2017 | The glycine hinge of transmembrane segment 2 modulates the subcellular localization and gating properties in TREK channels. | 4 |
| 25766236 | 2015 | K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac. | 150 |
| 25982558 | 2015 | Insights into the stimulatory mechanism of 2-aminoethoxydiphenyl borate on TREK-2 potassium channel. | 11 |
| 26271386 | 2015 | The isoforms generated by alternative translation initiation adopt similar conformation in the selectivity filter in TREK-2. | 4 |
| 26332952 | 2015 | How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2. | 45 |
| 26381449 | 2015 | The association of DNA methylation and brain volume in healthy individuals and schizophrenia patients. | 22 |
| 25766236 | 2015 | K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac. | 150 |
| 25982558 | 2015 | Insights into the stimulatory mechanism of 2-aminoethoxydiphenyl borate on TREK-2 potassium channel. | 11 |
| 26271386 | 2015 | The isoforms generated by alternative translation initiation adopt similar conformation in the selectivity filter in TREK-2. | 4 |
| 26332952 | 2015 | How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2. | 45 |
Citation
Dessen P
KCNK10 (potassium two pore domain channel subfamily K member 10)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/53925/kcnk10-(potassium-two-pore-domain-channel-subfamily-k-member-10)
