ZBTB1 (zinc finger and BTB domain containing 1)

2014-06-01  

Identity

HGNC
ZBTB1
LOCATION
14q23.3
LOCUSID
22890
ALIAS
ZNF909
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 22890
MIM: 616578
HGNC: 20259
Ensembl: ENSG00000126804

Variants:

dbSNP: 22890
ClinVar: 22890
TCGA: ENSG00000126804
COSMIC: ZBTB1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126804ENST00000358738Q9Y2K1
ENSG00000126804ENST00000553583G3V447
ENSG00000126804ENST00000554015Q9Y2K1
ENSG00000126804ENST00000555321G3V3N0
ENSG00000126804ENST00000556965G3V2I8

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
353941752022Circ_0000442 functions as a tumor repressor in breast cancer by impacting miR-1229-3p and upregulating ZBTB1.2
353941752022Circ_0000442 functions as a tumor repressor in breast cancer by impacting miR-1229-3p and upregulating ZBTB1.2
343129702021Preliminary analysis of the expression of ZBTB1 in human pancreatic carcinoma.1
343129702021Preliminary analysis of the expression of ZBTB1 in human pancreatic carcinoma.1
322681162020ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase.22
326906112020A novel tumor suppressor ZBTB1 regulates tamoxifen resistance and aerobic glycolysis through suppressing HER2 expression in breast cancer.11
322681162020ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase.22
326906112020A novel tumor suppressor ZBTB1 regulates tamoxifen resistance and aerobic glycolysis through suppressing HER2 expression in breast cancer.11
246571652014Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis.38
246571652014Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis.38
217061672011Novel human BTB/POZ domain-containing zinc finger protein ZBTB1 inhibits transcriptional activities of CRE.9
217061672011Novel human BTB/POZ domain-containing zinc finger protein ZBTB1 inhibits transcriptional activities of CRE.9

Citation

Dessen P

ZBTB1 (zinc finger and BTB domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/53927/zbtb1-(zinc-finger-and-btb-domain-containing-1)