SRRM4 (serine/arginine repetitive matrix 4)

2014-06-01  

Identity

HGNC
SRRM4
LOCATION
12q24.23
LOCUSID
84530
ALIAS
KIAA1853,MU-MB-2.76,nSR100
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84530
MIM: 613103
HGNC: 29389
Ensembl: ENSG00000139767

Variants:

dbSNP: 84530
ClinVar: 84530
TCGA: ENSG00000139767
COSMIC: SRRM4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139767ENST00000267260A7MD48
ENSG00000139767ENST00000267260V5T9A0
ENSG00000139767ENST00000641899A0A286YF08

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
343121802021RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer.21
343121802021RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer.21
324030542020Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4.16
332076942020SRRM4 Expands the Repertoire of Circular RNAs by Regulating Microexon Inclusion.7
324030542020Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4.16
332076942020SRRM4 Expands the Repertoire of Circular RNAs by Regulating Microexon Inclusion.7
301559922019SRRM4 gene expression correlates with neuroendocrine prostate cancer.19
309103472019RNA Splicing of the BHC80 Gene Contributes to Neuroendocrine Prostate Cancer Progression.13
311102842019A gapmer antisense oligonucleotide targeting SRRM4 is a novel therapeutic medicine for lung cancer.14
301559922019SRRM4 gene expression correlates with neuroendocrine prostate cancer.19
309103472019RNA Splicing of the BHC80 Gene Contributes to Neuroendocrine Prostate Cancer Progression.13
311102842019A gapmer antisense oligonucleotide targeting SRRM4 is a novel therapeutic medicine for lung cancer.14
297594852018Roles of Alternative RNA Splicing of the Bif-1 Gene by SRRM4 During the Development of Treatment-induced Neuroendocrine Prostate Cancer.12
301003952018A novel mechanism of SRRM4 in promoting neuroendocrine prostate cancer development via a pluripotency gene network.29
297594852018Roles of Alternative RNA Splicing of the Bif-1 Gene by SRRM4 During the Development of Treatment-induced Neuroendocrine Prostate Cancer.12

Citation

Dessen P

SRRM4 (serine/arginine repetitive matrix 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/53931/srrm4-(serine-arginine-repetitive-matrix-4)