Identity
HGNC
LOCATION
1q41
LOCUSID
ALIAS
K2p2.1,TPKC1,TREK,TREK-1,TREK1,hTREK-1c,hTREK-1e
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3776
MIM: 603219
HGNC: 6277
Ensembl: ENSG00000082482
Variants:
dbSNP: 3776
ClinVar: 3776
TCGA: ENSG00000082482
COSMIC: KCNK2
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36410022 | 2023 | Activation of TREK-1 (K(2P)2.1) potassium channels protects against influenza A-induced lung injury. | 3 |
| 36909311 | 2023 | High glucose induced HIF-1α/TREK1 expression and myometrium relaxation during pregnancy. | 0 |
| 37014157 | 2023 | miR-132-3p promotes heat stimulation-induced esophageal squamous cell carcinoma tumorigenesis by targeting KCNK2. | 1 |
| 37184053 | 2023 | Prolonged stretching of rat uteri causes hypoxia and inhibits contractility via potassium channel TREK1. | 0 |
| 36410022 | 2023 | Activation of TREK-1 (K(2P)2.1) potassium channels protects against influenza A-induced lung injury. | 3 |
| 36909311 | 2023 | High glucose induced HIF-1α/TREK1 expression and myometrium relaxation during pregnancy. | 0 |
| 37014157 | 2023 | miR-132-3p promotes heat stimulation-induced esophageal squamous cell carcinoma tumorigenesis by targeting KCNK2. | 1 |
| 37184053 | 2023 | Prolonged stretching of rat uteri causes hypoxia and inhibits contractility via potassium channel TREK1. | 0 |
| 35177207 | 2022 | Involvement of TREK1 channels in the proliferation of human hepatic stellate LX-2 cells. | 2 |
| 35177207 | 2022 | Involvement of TREK1 channels in the proliferation of human hepatic stellate LX-2 cells. | 2 |
| 33025137 | 2021 | Intracellular activation of full-length human TREK-1 channel by hypoxia, high lactate, and low pH denotes polymodal integration by ischemic factors. | 3 |
| 34038243 | 2021 | Human adrenal glomerulosa cells express K2P and GIRK potassium channels that are inhibited by ANG II and ACTH. | 4 |
| 33025137 | 2021 | Intracellular activation of full-length human TREK-1 channel by hypoxia, high lactate, and low pH denotes polymodal integration by ischemic factors. | 3 |
| 34038243 | 2021 | Human adrenal glomerulosa cells express K2P and GIRK potassium channels that are inhibited by ANG II and ACTH. | 4 |
| 31782179 | 2020 | Astrocytic AEG-1 regulates expression of TREK-1 under acute hypoxia. | 3 |
Citation
Dessen P
KCNK2 (potassium two pore domain channel subfamily K member 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/53934/kcnk2-(potassium-two-pore-domain-channel-subfamily-k-member-2)
