Identity
HGNC
LOCATION
11p15.5
LOCUSID
ALIAS
PPP1R125,RNF221
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57661
MIM: 611780
HGNC: 24351
Ensembl: ENSG00000070047
Variants:
dbSNP: 57661
ClinVar: 57661
TCGA: ENSG00000070047
COSMIC: PHRF1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38030167 | 2023 | PHRF1 Promotes Cell Invasion by Modulating SOX4 Expression in Colorectal Cancer HCT116-p53(-/-) Cells. | 0 |
| 38030167 | 2023 | PHRF1 Promotes Cell Invasion by Modulating SOX4 Expression in Colorectal Cancer HCT116-p53(-/-) Cells. | 0 |
| 32360246 | 2020 | Downregulation of a putative tumor suppressor gene PHRF1 in gastric and colorectal cancers. | 0 |
| 32360246 | 2020 | Downregulation of a putative tumor suppressor gene PHRF1 in gastric and colorectal cancers. | 0 |
| 27608840 | 2016 | Overexpression of PHRF1 attenuates the proliferation and tumorigenicity of non-small cell lung cancer cells. | 4 |
| 27608840 | 2016 | Overexpression of PHRF1 attenuates the proliferation and tumorigenicity of non-small cell lung cancer cells. | 4 |
| 25855964 | 2015 | PHRF1 promotes genome integrity by modulating non-homologous end-joining. | 21 |
| 25855964 | 2015 | PHRF1 promotes genome integrity by modulating non-homologous end-joining. | 21 |
| 23911286 | 2013 | Identification of PHRF1 as a tumor suppressor that promotes the TGF-β cytostatic program through selective release of TGIF-driven PML inactivation. | 20 |
| 23911286 | 2013 | Identification of PHRF1 as a tumor suppressor that promotes the TGF-β cytostatic program through selective release of TGIF-driven PML inactivation. | 20 |
| 22433914 | 2012 | Association of PHRF1-IRF7 region polymorphism with clinical manifestations of systemic lupus erythematosus in a Japanese population. | 10 |
| 22433914 | 2012 | Association of PHRF1-IRF7 region polymorphism with clinical manifestations of systemic lupus erythematosus in a Japanese population. | 10 |
| 20881011 | 2011 | Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients. | 65 |
| 20962850 | 2011 | A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles. | 25 |
| 21068098 | 2011 | Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus. | 69 |
Citation
Dessen P
PHRF1 (PHD and ring finger domains 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/53938/phrf1-(phd-and-ring-finger-domains-1)
