ADGRE3 (adhesion G protein-coupled receptor E3)

2014-06-01  

Identity

HGNC
LOCATION
19p13.12
LOCUSID
ALIAS
EMR3

Other Information

Locus ID:

NCBI: 84658
MIM: 606101
HGNC: 23647
Ensembl: ENSG00000131355

Variants:

dbSNP: 84658
ClinVar: 84658
TCGA: ENSG00000131355
COSMIC: ADGRE3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131355ENST00000253673Q9BY15
ENSG00000131355ENST00000344373Q9BY15
ENSG00000131355ENST00000443157E7EW83
ENSG00000131355ENST00000595472M0QYN7
ENSG00000131355ENST00000599900M0R1G2

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class B/2 (Secretin family receptors)REACTOMER-HSA-373080
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
206255112010Gene transcription changes in asthmatic chronic rhinosinusitis with nasal polyps and comparison to those in atopic dermatitis.17
171080562007The human EGF-TM7 receptor EMR3 is a marker for mature granulocytes.14
208272262010EMR-3: a potential mediator of invasive phenotypic variation in glioblastoma and novel therapeutic target.8

Citation

Dessen P

ADGRE3 (adhesion G protein-coupled receptor E3)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/53952/adgre3-(adhesion-g-protein-coupled-receptor-e3)