Identity
HGNC
LOCATION
1p22.3
LOCUSID
ALIAS
DDAH,DDAH-1,DDAHI,HEL-S-16
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23576
MIM: 604743
HGNC: 2715
Ensembl: ENSG00000153904
Variants:
dbSNP: 23576
ClinVar: 23576
TCGA: ENSG00000153904
COSMIC: DDAH1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism | REACTOME | R-HSA-1430728 |
| Metabolism of nitric oxide | REACTOME | R-HSA-202131 |
| eNOS activation and regulation | REACTOME | R-HSA-203765 |
| eNOS activation | REACTOME | R-HSA-203615 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36400179 | 2023 | Genome-wide admixture and association analysis identifies African ancestry-specific risk loci of eosinophilic esophagitis in African Americans. | 4 |
| 37116560 | 2023 | LncRNA DANCR deficiency promotes high glucose-induced endothelial to mesenchymal transition in cardiac microvascular cells via the FoxO1/DDAH1/ADMA signaling pathway. | 1 |
| 37423418 | 2023 | Dimethylarginine Dimethylaminohydrolase - 1 expression is increased under tBHP-induced oxidative stress regulates nitric oxide production in PCa cells attenuates mitochondrial ROS-mediated apoptosis. | 1 |
| 36400179 | 2023 | Genome-wide admixture and association analysis identifies African ancestry-specific risk loci of eosinophilic esophagitis in African Americans. | 4 |
| 37116560 | 2023 | LncRNA DANCR deficiency promotes high glucose-induced endothelial to mesenchymal transition in cardiac microvascular cells via the FoxO1/DDAH1/ADMA signaling pathway. | 1 |
| 37423418 | 2023 | Dimethylarginine Dimethylaminohydrolase - 1 expression is increased under tBHP-induced oxidative stress regulates nitric oxide production in PCa cells attenuates mitochondrial ROS-mediated apoptosis. | 1 |
| 35598478 | 2022 | On the kinetic mechanism of dimethylarginine dimethylaminohydrolase. | 0 |
| 36233204 | 2022 | Assessment of DDAH1 and DDAH2 Contributions to Psychiatric Disorders via In Silico Methods. | 0 |
| 36461077 | 2022 | The effect of haptoglobin genotype on the association of asymmetric dimethylarginine and DDAH 1 polymorphism with diabetic macroangiopathy. | 0 |
| 35598478 | 2022 | On the kinetic mechanism of dimethylarginine dimethylaminohydrolase. | 0 |
| 36233204 | 2022 | Assessment of DDAH1 and DDAH2 Contributions to Psychiatric Disorders via In Silico Methods. | 0 |
| 36461077 | 2022 | The effect of haptoglobin genotype on the association of asymmetric dimethylarginine and DDAH 1 polymorphism with diabetic macroangiopathy. | 0 |
| 33849119 | 2021 | Abnormalities of the PRMT1-ADMA-DDAH1 metabolism axis and probucol treatment in diabetic patients and diabetic rats. | 3 |
| 33849119 | 2021 | Abnormalities of the PRMT1-ADMA-DDAH1 metabolism axis and probucol treatment in diabetic patients and diabetic rats. | 3 |
| 31503013 | 2020 | Long non-coding RNA H19 confers resistance to gefitinib via miR-148b-3p/DDAH1 axis in lung adenocarcinoma. | 12 |
Citation
Dessen P
DDAH1 (dimethylarginine dimethylaminohydrolase 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/53958/ddah1-(dimethylarginine-dimethylaminohydrolase-1)
