ARL4A (ADP ribosylation factor like GTPase 4A)

2014-06-01  

Identity

HGNC
ARL4A
LOCATION
7p21.3
LOCUSID
10124
ALIAS
ARL4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10124
MIM: 604786
HGNC: 695
Ensembl: ENSG00000122644

Variants:

dbSNP: 10124
ClinVar: 10124
TCGA: ENSG00000122644
COSMIC: ARL4A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122644ENST00000356797P40617
ENSG00000122644ENST00000356797A0A024R9Z2
ENSG00000122644ENST00000396662P40617
ENSG00000122644ENST00000396662A0A024R9Z2
ENSG00000122644ENST00000396663P40617
ENSG00000122644ENST00000396663A0A024R9Z2
ENSG00000122644ENST00000396664P40617
ENSG00000122644ENST00000396664A0A024R9Z2
ENSG00000122644ENST00000404894P40617
ENSG00000122644ENST00000404894A0A024R9Z2
ENSG00000122644ENST00000439721C9J7Q9
ENSG00000122644ENST00000651779P40617
ENSG00000122644ENST00000651779A0A024R9Z2

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
358578682022Phosphorylation of Arl4A/D promotes their binding by the HYPK chaperone for their stable recruitment to the plasma membrane.3
358578682022Phosphorylation of Arl4A/D promotes their binding by the HYPK chaperone for their stable recruitment to the plasma membrane.3
304277592019ADP-ribosylation factor-like 4A interacts with Robo1 to promote cell migration by regulating Cdc42 activation.7
304277592019ADP-ribosylation factor-like 4A interacts with Robo1 to promote cell migration by regulating Cdc42 activation.7
219307032011The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family.30
221594192011ARL4A acts with GCC185 to modulate Golgi complex organization.20
219307032011The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family.30
221594192011ARL4A acts with GCC185 to modulate Golgi complex organization.20
182409262008Increased expression of the glioma-associated antigen ARF4L after loss of the tumor suppressor PTEN. Laboratory investigation.9
182409262008Increased expression of the glioma-associated antigen ARF4L after loss of the tumor suppressor PTEN. Laboratory investigation.9
173980952007The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane.63
173980952007The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane.63

Citation

Dessen P

ARL4A (ADP ribosylation factor like GTPase 4A)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/53967/arl4a-(adp-ribosylation-factor-like-gtpase-4a)