Identity
HGNC
LOCATION
8p21.1
LOCUSID
ALIAS
N/OFQ,NOP,OFQ,PPNOC,ppN/OFQ
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5368
MIM: 601459
HGNC: 9163
Ensembl: ENSG00000168081
Variants:
dbSNP: 5368
ClinVar: 5368
TCGA: ENSG00000168081
COSMIC: PNOC
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168081 | ENST00000301908 | Q13519 |
| ENSG00000168081 | ENST00000518479 | E7EVP0 |
| ENSG00000168081 | ENST00000522209 | Q13519 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33841428 | 2021 | PNOC Expressed by B Cells in Cholangiocarcinoma Was Survival Related and LAIR2 Could Be a T Cell Exhaustion Biomarker in Tumor Microenvironment: Characterization of Immune Microenvironment Combining Single-Cell and Bulk Sequencing Technology. | 25 |
| 33841428 | 2021 | PNOC Expressed by B Cells in Cholangiocarcinoma Was Survival Related and LAIR2 Could Be a T Cell Exhaustion Biomarker in Tumor Microenvironment: Characterization of Immune Microenvironment Combining Single-Cell and Bulk Sequencing Technology. | 25 |
| 27983768 | 2017 | Association of maternal and infant variants in PNOC and COMT genes with neonatal abstinence syndrome severity. | 16 |
| 27983768 | 2017 | Association of maternal and infant variants in PNOC and COMT genes with neonatal abstinence syndrome severity. | 16 |
| 26791055 | 2016 | Neonatal abstinence syndrome: Pharmacologic strategies for the mother and infant. | 31 |
| 26791055 | 2016 | Neonatal abstinence syndrome: Pharmacologic strategies for the mother and infant. | 31 |
| 25677768 | 2015 | Bioinformatics and evolution of vertebrate nociceptin and opioid receptors. | 5 |
| 25677772 | 2015 | Nociceptin and meiosis during spermatogenesis in postnatal testes. | 6 |
| 25677773 | 2015 | Orphanin FQ-ORL-1 regulation of reproduction and reproductive behavior in the female. | 6 |
| 25677774 | 2015 | Effects of nociceptin and nocistatin on uterine contraction. | 1 |
| 25677775 | 2015 | Nociceptin/orphanin FQ-NOP receptor system in inflammatory and immune-mediated diseases. | 15 |
| 25677776 | 2015 | Endogenous nociceptin system involvement in stress responses and anxiety behavior. | 2 |
| 25677777 | 2015 | The neuronal circuit between nociceptin/orphanin FQ and hypocretins/orexins coordinately modulates stress-induced analgesia and anxiety-related behavior. | 0 |
| 25677778 | 2015 | Nociceptin/orphanin-FQ modulation of learning and memory. | 2 |
| 26233486 | 2015 | Variations in opioid receptor genes in neonatal abstinence syndrome. | 22 |
Citation
Dessen P
PNOC (prepronociceptin)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/53968/pnoc-(prepronociceptin)
