Identity
HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
AROS,S19BP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 91582
MIM: 610225
HGNC: 28749
Ensembl: ENSG00000187051
Variants:
dbSNP: 91582
ClinVar: 91582
TCGA: ENSG00000187051
COSMIC: RPS19BP1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000187051 | ENST00000334678 | Q86WX3 |
| ENSG00000187051 | ENST00000334678 | A0A024R1T1 |
| ENSG00000187051 | ENST00000420879 | F8WFE7 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cellular responses to stress | REACTOME | R-HSA-2262752 |
| Cellular response to heat stress | REACTOME | R-HSA-3371556 |
| Regulation of HSF1-mediated heat shock response | REACTOME | R-HSA-3371453 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36361557 | 2022 | Molecular Mechanism of Sirtuin 1 Modulation by the AROS Protein. | 1 |
| 36361557 | 2022 | Molecular Mechanism of Sirtuin 1 Modulation by the AROS Protein. | 1 |
| 29733858 | 2018 | The Legionella pneumophila Methyltransferase RomA Methylates Also Non-histone Proteins during Infection. | 8 |
| 29733858 | 2018 | The Legionella pneumophila Methyltransferase RomA Methylates Also Non-histone Proteins during Infection. | 8 |
| 26339164 | 2015 | AROS Is a Significant Biomarker for Tumor Aggressiveness in Non-cirrhotic Hepatocellular Carcinoma. | 2 |
| 26339164 | 2015 | AROS Is a Significant Biomarker for Tumor Aggressiveness in Non-cirrhotic Hepatocellular Carcinoma. | 2 |
| 24681097 | 2014 | AROS has a context-dependent effect on SIRT1. | 8 |
| 24681097 | 2014 | AROS has a context-dependent effect on SIRT1. | 8 |
| 23349863 | 2013 | The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response. | 25 |
| 23548308 | 2013 | Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol. | 18 |
| 24258275 | 2013 | Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity. | 16 |
| 23349863 | 2013 | The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response. | 25 |
| 23548308 | 2013 | Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol. | 18 |
| 24258275 | 2013 | Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity. | 16 |
| 17964266 | 2007 | Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity. | 197 |
Citation
Dessen P
RPS19BP1 (ribosomal protein S19 binding protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/53979/rps19bp1-(ribosomal-protein-s19-binding-protein-1)
