Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1129
MIM: 118493
HGNC: 1951
Ensembl: ENSG00000181072
Variants:
dbSNP: 1129
ClinVar: 1129
TCGA: ENSG00000181072
COSMIC: CHRM2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA445876 | Tobacco Use Disorder | Disease | ClinicalAnnotation | associated | PD | 19644963 | |
| PA450626 | nicotine | Chemical | ClinicalAnnotation | associated | PD | 19644963 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38185384 | 2024 | M2 muscarinic receptors negatively modulate cell migration in human glioblastoma cells. | 1 |
| 38683874 | 2024 | The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions. | 0 |
| 38185384 | 2024 | M2 muscarinic receptors negatively modulate cell migration in human glioblastoma cells. | 1 |
| 38683874 | 2024 | The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions. | 0 |
| 34359896 | 2021 | M2 Muscarinic Receptor Activation Impairs Mitotic Progression and Bipolar Mitotic Spindle Formation in Human Glioblastoma Cell Lines. | 5 |
| 34390568 | 2021 | Deep learning-based classification of breast cancer cells using transmembrane receptor dynamics. | 2 |
| 34815515 | 2021 | Vibrational spectroscopy analysis of ligand efficacy in human M(2) muscarinic acetylcholine receptor (M(2)R). | 3 |
| 34359896 | 2021 | M2 Muscarinic Receptor Activation Impairs Mitotic Progression and Bipolar Mitotic Spindle Formation in Human Glioblastoma Cell Lines. | 5 |
| 34390568 | 2021 | Deep learning-based classification of breast cancer cells using transmembrane receptor dynamics. | 2 |
| 34815515 | 2021 | Vibrational spectroscopy analysis of ligand efficacy in human M(2) muscarinic acetylcholine receptor (M(2)R). | 3 |
| 30623717 | 2020 | Pharmacogenetics of tardive dyskinesia in schizophrenia: The role of CHRM1 and CHRM2 muscarinic receptors. | 4 |
| 32080232 | 2020 | Modeling the allosteric modulation on a G-Protein Coupled Receptor: the case of M2 muscarinic Acetylcholine Receptor in complex with LY211960. | 1 |
| 32182759 | 2020 | Cross Interaction between M2 Muscarinic Receptor and Notch1/EGFR Pathway in Human Glioblastoma Cancer Stem Cells: Effects on Cell Cycle Progression and Survival. | 13 |
| 32234387 | 2020 | Group II muscarinic acetylcholine receptors attenuate hepatic injury via Nrf2/ARE pathway. | 2 |
| 30623717 | 2020 | Pharmacogenetics of tardive dyskinesia in schizophrenia: The role of CHRM1 and CHRM2 muscarinic receptors. | 4 |
Citation
Dessen P
CHRM2 (cholinergic receptor muscarinic 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/53984/chrm2-(cholinergic-receptor-muscarinic-2)
