Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7201
MIM: 188545
HGNC: 12299
Ensembl: ENSG00000174417
Variants:
dbSNP: 7201
ClinVar: 7201
TCGA: ENSG00000174417
COSMIC: TRHR
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000174417 | ENST00000311762 | P34981 |
| ENSG00000174417 | ENST00000518632 | P34981 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29137494 | 2018 | TRH receptor mobility in the plasma membrane is strongly affected by agonist binding and by interaction with some cognate signaling proteins. | 1 |
| 29137494 | 2018 | TRH receptor mobility in the plasma membrane is strongly affected by agonist binding and by interaction with some cognate signaling proteins. | 1 |
| 28419241 | 2017 | Central Hypothyroidism Due to a TRHR Mutation Causing Impaired Ligand Affinity and Transactivation of Gq. | 11 |
| 28419241 | 2017 | Central Hypothyroidism Due to a TRHR Mutation Causing Impaired Ligand Affinity and Transactivation of Gq. | 11 |
| 23543262 | 2013 | Association between polymorphisms in the TRHR gene, fat-free mass, and muscle strength in older women. | 4 |
| 23543262 | 2013 | Association between polymorphisms in the TRHR gene, fat-free mass, and muscle strength in older women. | 4 |
| 22240728 | 2012 | Identification of a preassembled TRH receptor-G(q/11) protein complex in HEK293 cells. | 3 |
| 22240728 | 2012 | Identification of a preassembled TRH receptor-G(q/11) protein complex in HEK293 cells. | 3 |
| 19906838 | 2010 | Role of helix 8 of the thyrotropin-releasing hormone receptor in phosphorylation by G protein-coupled receptor kinase. | 17 |
| 20345371 | 2010 | Importance of regions outside the cytoplasmic tail of G-protein-coupled receptors for phosphorylation and dephosphorylation. | 8 |
| 19906838 | 2010 | Role of helix 8 of the thyrotropin-releasing hormone receptor in phosphorylation by G protein-coupled receptor kinase. | 17 |
| 20345371 | 2010 | Importance of regions outside the cytoplasmic tail of G-protein-coupled receptors for phosphorylation and dephosphorylation. | 8 |
| 19086053 | 2009 | Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. | 39 |
| 19268274 | 2009 | Genome-wide association and replication studies identified TRHR as an important gene for lean body mass. | 52 |
| 19268274 | 2009 | Genome-wide association and replication studies identified TRHR as an important gene for lean body mass. | 52 |
Citation
Dessen P
TRHR (thyrotropin releasing hormone receptor)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/53994/gene-fusions/gene-fusions-explorer/
