Identity
HGNC
LOCATION
17q23.3
LOCUSID
ALIAS
ERG-2,ERG2,HERG2,Kv11.2,hERG-2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 81033
MIM: 608168
HGNC: 18862
Ensembl: ENSG00000173826
Variants:
dbSNP: 81033
ClinVar: 81033
TCGA: ENSG00000173826
COSMIC: KCNH6
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuronal System | REACTOME | R-HSA-112316 |
| Potassium Channels | REACTOME | R-HSA-1296071 |
| Voltage gated Potassium channels | REACTOME | R-HSA-1296072 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35818223 | 2022 | Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome. | 0 |
| 36217412 | 2022 | KCNH6 Enhanced Hepatic Glucose Metabolism through Mitochondrial Ca(2+) Regulation and Oxidative Stress Inhibition. | 0 |
| 35818223 | 2022 | Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome. | 0 |
| 36217412 | 2022 | KCNH6 Enhanced Hepatic Glucose Metabolism through Mitochondrial Ca(2+) Regulation and Oxidative Stress Inhibition. | 0 |
| 34529278 | 2021 | Prostate tumors of native men from West Africa show biologically distinct pathways-A comparative genomic study. | 4 |
| 34556670 | 2021 | Berberine is an insulin secretagogue targeting the KCNH6 potassium channel. | 25 |
| 34529278 | 2021 | Prostate tumors of native men from West Africa show biologically distinct pathways-A comparative genomic study. | 4 |
| 34556670 | 2021 | Berberine is an insulin secretagogue targeting the KCNH6 potassium channel. | 25 |
| 30590050 | 2018 | From Hyper- to Hypoinsulinemia and Diabetes: Effect of KCNH6 on Insulin Secretion. | 22 |
| 30590050 | 2018 | From Hyper- to Hypoinsulinemia and Diabetes: Effect of KCNH6 on Insulin Secretion. | 22 |
| 25783051 | 2015 | MicroRNA-224 targets ERG2 and contributes to malignant progressions of meningioma. | 17 |
| 25783051 | 2015 | MicroRNA-224 targets ERG2 and contributes to malignant progressions of meningioma. | 17 |
| 21048031 | 2011 | Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. | 5 |
| 21048031 | 2011 | Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. | 5 |
| 12634931 | 2003 | HERG K(+) currents in human prolactin-secreting adenoma cells. | 13 |
Citation
Dessen P
KCNH6 (potassium voltage-gated channel subfamily H member 6)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/53998/kcnh6-(potassium-voltage-gated-channel-subfamily-h-member-6)
