TREH (trehalase)

2014-06-01  

Identity

HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
TRE,TREA,TREHD
FUSION GENES

Other Information

Locus ID:

NCBI: 11181
MIM: 275360
HGNC: 12266
Ensembl: ENSG00000118094

Variants:

dbSNP: 11181
ClinVar: 11181
TCGA: ENSG00000118094
COSMIC: TREH

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118094ENST00000264029O43280
ENSG00000118094ENST00000397925O43280
ENSG00000118094ENST00000613915A0A087WTJ4

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Starch and sucrose metabolismKEGGko00500
Starch and sucrose metabolismKEGGhsa00500
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Digestion of dietary carbohydrateREACTOMER-HSA-189085

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
289811172017Trehalose ameliorates oxidative stress-mediated mitochondrial dysfunction and ER stress via selective autophagy stimulation and autophagic flux restoration in osteoarthritis development.98
289811172017Trehalose ameliorates oxidative stress-mediated mitochondrial dysfunction and ER stress via selective autophagy stimulation and autophagic flux restoration in osteoarthritis development.98
277014242016Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.42
277014242016Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.42
261563972015Association between RTEL1, PHLDB1, and TREH Polymorphisms and Glioblastoma Risk: A Case-Control Study.5
261563972015Association between RTEL1, PHLDB1, and TREH Polymorphisms and Glioblastoma Risk: A Case-Control Study.5
234681752013Identification of genetic variation that determines human trehalase activity and its association with type 2 diabetes.11
234681752013Identification of genetic variation that determines human trehalase activity and its association with type 2 diabetes.11
223697352012Polymorphisms of TREH, IL4R and CCDC26 genes associated with risk of glioma.30
223697352012Polymorphisms of TREH, IL4R and CCDC26 genes associated with risk of glioma.30
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
191264022009Human trehalase is a stress responsive protein in Saccharomyces cerevisiae.9
191264022009Human trehalase is a stress responsive protein in Saccharomyces cerevisiae.9

Citation

Dessen P

TREH (trehalase)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/54001/treh-(trehalase)