Identity
HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
BTL-II,BTN7,HSBLMHC1,SS2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56244
MIM: 606000
HGNC: 1142
Ensembl: ENSG00000204290
Variants:
dbSNP: 56244
ClinVar: 56244
TCGA: ENSG00000204290
COSMIC: BTNL2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Adaptive Immune System | REACTOME | R-HSA-1280218 |
| Butyrophilin (BTN) family interactions | REACTOME | R-HSA-8851680 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35017553 | 2022 | Cancer cell-expressed BTNL2 facilitates tumour immune escape via engagement with IL-17A-producing γδ T cells. | 16 |
| 35017553 | 2022 | Cancer cell-expressed BTNL2 facilitates tumour immune escape via engagement with IL-17A-producing γδ T cells. | 16 |
| 34871226 | 2021 | Genome-wide association study identifies BTNL2 associated with atopic asthma in children. | 2 |
| 34871226 | 2021 | Genome-wide association study identifies BTNL2 associated with atopic asthma in children. | 2 |
| 31605414 | 2020 | Association of GWAS-supported noncoding area loci rs404860, rs3117098, and rs7775228 with asthma in Chinese Zhuang population. | 2 |
| 33022050 | 2020 | Shared Signature of Recent Positive Selection on the TSBP1-BTNL2-HLA-DRA Genes in Five Native Populations from North Borneo. | 2 |
| 31605414 | 2020 | Association of GWAS-supported noncoding area loci rs404860, rs3117098, and rs7775228 with asthma in Chinese Zhuang population. | 2 |
| 33022050 | 2020 | Shared Signature of Recent Positive Selection on the TSBP1-BTNL2-HLA-DRA Genes in Five Native Populations from North Borneo. | 2 |
| 30872286 | 2019 | BTNL2 gene polymorphism and sarcoid uveitis. | 7 |
| 31624234 | 2019 | Chromatin profiling of cortical neurons identifies individual epigenetic signatures in schizophrenia. | 12 |
| 30872286 | 2019 | BTNL2 gene polymorphism and sarcoid uveitis. | 7 |
| 31624234 | 2019 | Chromatin profiling of cortical neurons identifies individual epigenetic signatures in schizophrenia. | 12 |
| 29733354 | 2018 | Deep Resequencing of Ulcerative Colitis-Associated Genes Identifies Novel Variants in Candidate Genes in the Korean Population. | 4 |
| 29733354 | 2018 | Deep Resequencing of Ulcerative Colitis-Associated Genes Identifies Novel Variants in Candidate Genes in the Korean Population. | 4 |
| 28025329 | 2017 | Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations. | 39 |
Citation
Dessen P
BTNL2 (butyrophilin like 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/54003/btnl2-(butyrophilin-like-2)
