Identity
HGNC
LOCATION
2q24.2
LOCUSID
ALIAS
ERG3,HERG3,Kv11.3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 90134
MIM: 608169
HGNC: 18863
Ensembl: ENSG00000184611
Variants:
dbSNP: 90134
ClinVar: 90134
TCGA: ENSG00000184611
COSMIC: KCNH7
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000184611 | ENST00000328032 | Q9NS40 |
| ENSG00000184611 | ENST00000332142 | Q9NS40 |
| ENSG00000184611 | ENST00000618399 | A0A087WZQ1 |
| ENSG00000184611 | ENST00000621889 | A0A087X077 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuronal System | REACTOME | R-HSA-112316 |
| Potassium Channels | REACTOME | R-HSA-1296071 |
| Voltage gated Potassium channels | REACTOME | R-HSA-1296072 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35818223 | 2022 | Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome. | 0 |
| 35818223 | 2022 | Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome. | 0 |
| 32723862 | 2020 | Discovery of a heme-binding domain in a neuronal voltage-gated potassium channel. | 13 |
| 32723862 | 2020 | Discovery of a heme-binding domain in a neuronal voltage-gated potassium channel. | 13 |
| 30016551 | 2018 | ERG3 potassium channel-mediated suppression of neuronal intrinsic excitability and prevention of seizure generation in mice. | 6 |
| 30016551 | 2018 | ERG3 potassium channel-mediated suppression of neuronal intrinsic excitability and prevention of seizure generation in mice. | 6 |
| 26942884 | 2016 | Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma. | 22 |
| 26942884 | 2016 | Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma. | 22 |
| 24986916 | 2014 | A population-based study of KCNH7 p.Arg394His and bipolar spectrum disorder. | 27 |
| 24986916 | 2014 | A population-based study of KCNH7 p.Arg394His and bipolar spectrum disorder. | 27 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19156166 | 2009 | IFIH1-GCA-KCNH7 locus is not associated with genetic susceptibility to multiple sclerosis in French patients. | 6 |
Citation
Dessen P
KCNH7 (potassium voltage-gated channel subfamily H member 7)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/54005/kcnh7-(potassium-voltage-gated-channel-subfamily-h-member-7)
