PHLDB1 (pleckstrin homology like domain family B member 1)

2014-06-01  

Identity

HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
LL5A
FUSION GENES

Other Information

Locus ID:

NCBI: 23187
MIM: 612834
HGNC: 23697
Ensembl: ENSG00000019144

Variants:

dbSNP: 23187
ClinVar: 23187
TCGA: ENSG00000019144
COSMIC: PHLDB1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000019144ENST00000356063Q86UU1
ENSG00000019144ENST00000356063A0A024R3F4
ENSG00000019144ENST00000361417Q86UU1
ENSG00000019144ENST00000361417A0A024R3H6
ENSG00000019144ENST00000528594Q86UU1
ENSG00000019144ENST00000530708A0A087WXY7
ENSG00000019144ENST00000530994Q86UU1
ENSG00000019144ENST00000532639A0A087WTZ7
ENSG00000019144ENST00000534140A0A087WZL0
ENSG00000019144ENST00000600882Q86UU1
ENSG00000019144ENST00000600882A0A024R3H6

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
365435342023Biallelic frameshift variants in PHLDB1 cause mild-type osteogenesis imperfecta with regressive spondylometaphyseal changes.0
365435342023Biallelic frameshift variants in PHLDB1 cause mild-type osteogenesis imperfecta with regressive spondylometaphyseal changes.0
351886042022Analysis of WDFY4 rs7097397 and PHLDB1 rs7389 polymorphisms in Chinese patients with systemic lupus erythematosus.0
351886042022Analysis of WDFY4 rs7097397 and PHLDB1 rs7389 polymorphisms in Chinese patients with systemic lupus erythematosus.0
317210212020Replication of GWAS identifies RTEL1, CDKN2A/B, and PHLDB1 SNPs as risk factors in Portuguese gliomas patients.6
317210212020Replication of GWAS identifies RTEL1, CDKN2A/B, and PHLDB1 SNPs as risk factors in Portuguese gliomas patients.6
308683562019A PHLDB1 variant associated with the nonfunctional pituitary adenoma.2
3092864920193'UTR variants of TNS3, PHLDB1, NTN4, and GNG2 genes are associated with IgA nephropathy risk in Chinese Han population.8
312153772019Role of Polymorphisms of FAM13A, PHLDB1, and CYP24A1 in Breast Cancer Risk.4
308683562019A PHLDB1 variant associated with the nonfunctional pituitary adenoma.2
3092864920193'UTR variants of TNS3, PHLDB1, NTN4, and GNG2 genes are associated with IgA nephropathy risk in Chinese Han population.8
312153772019Role of Polymorphisms of FAM13A, PHLDB1, and CYP24A1 in Breast Cancer Risk.4
293484172018Identification of a membrane-less compartment regulating invadosome function and motility.13
293484172018Identification of a membrane-less compartment regulating invadosome function and motility.13
288863072017Pleckstrin homology-like domain family B member 1 rs498872 polymorphism and glioma risk in Chinese Han population.0

Citation

Dessen P

PHLDB1 (pleckstrin homology like domain family B member 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/54007/phldb1-(pleckstrin-homology-like-domain-family-b-member-1)