Identity
HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
CLCRP1,DSI,ERBA2L,GIT,P4Hbeta,PDI,PDIA1,PHDB,PO4DB,PO4HB,PROHB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5034
MIM: 176790
HGNC: 8548
Ensembl: ENSG00000185624
Variants:
dbSNP: 5034
ClinVar: 5034
TCGA: ENSG00000185624
COSMIC: P4HB
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38100120 | 2024 | ARID1A loss induces P4HB to activate fibroblasts to support lung cancer cell growth, invasion, and chemoresistance. | 2 |
| 38396772 | 2024 | Exploring the Influence of Zinc Ions on the Conformational Stability and Activity of Protein Disulfide Isomerase. | 0 |
| 38100120 | 2024 | ARID1A loss induces P4HB to activate fibroblasts to support lung cancer cell growth, invasion, and chemoresistance. | 2 |
| 38396772 | 2024 | Exploring the Influence of Zinc Ions on the Conformational Stability and Activity of Protein Disulfide Isomerase. | 0 |
| 35984546 | 2023 | Protein disulfide isomerase A1 as a novel redox sensor in VEGFR2 signaling and angiogenesis. | 4 |
| 36463755 | 2023 | A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes. | 6 |
| 37119730 | 2023 | A meta-analysis and bioinformatics analysis of P4HB expression levels in the prognosis of cancer patients. | 2 |
| 37807312 | 2023 | MiR-204-5p regulates HUVEC cell inflammation and apoptosis by targeting P4HB. | 0 |
| 37845668 | 2023 | Establishment of prognostic model of bladder cancer based on apoptosis-related genes, in which P4HB promotes BLCA progression. | 0 |
| 37880717 | 2023 | Circular RNA P4HB promotes glycolysis and tumor progression by binding with PKM2 in lung adenocarcinoma. | 2 |
| 35984546 | 2023 | Protein disulfide isomerase A1 as a novel redox sensor in VEGFR2 signaling and angiogenesis. | 4 |
| 36463755 | 2023 | A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes. | 6 |
| 37119730 | 2023 | A meta-analysis and bioinformatics analysis of P4HB expression levels in the prognosis of cancer patients. | 2 |
| 37807312 | 2023 | MiR-204-5p regulates HUVEC cell inflammation and apoptosis by targeting P4HB. | 0 |
| 37845668 | 2023 | Establishment of prognostic model of bladder cancer based on apoptosis-related genes, in which P4HB promotes BLCA progression. | 0 |
Citation
Dessen P
P4HB (prolyl 4-hydroxylase subunit beta)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/54011/p4hb-(prolyl-4-hydroxylase-subunit-beta)
