INTS4 (integrator complex subunit 4)

2014-06-01  

Identity

HGNC
INTS4
LOCATION
11q14.1
LOCUSID
92105
ALIAS
INT4,MST093
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 92105
MIM: 611348
HGNC: 25048
Ensembl: ENSG00000149262

Variants:

dbSNP: 92105
ClinVar: 92105
TCGA: ENSG00000149262
COSMIC: INTS4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149262ENST00000433818F8WAA7
ENSG00000149262ENST00000524766E9PIM3
ENSG00000149262ENST00000527522E9PIM3
ENSG00000149262ENST00000529807Q96HW7
ENSG00000149262ENST00000534064Q96HW7
ENSG00000149262ENST00000534408E9PIM3
ENSG00000149262ENST00000535943Q96HW7

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA polymerase II transcribes snRNA genesREACTOMER-HSA-6807505

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
bone marrow

References

Pubmed IDYearTitleCitations
294713652018Integrator subunit 4 is a 'Symplekin-like' scaffold that associates with INTS9/11 to form the Integrator cleavage module.43
294713652018Integrator subunit 4 is a 'Symplekin-like' scaffold that associates with INTS9/11 to form the Integrator cleavage module.43
222501972012The integrator complex is required for integrity of Cajal bodies.29
222501972012The integrator complex is required for integrity of Cajal bodies.29

Citation

Dessen P

INTS4 (integrator complex subunit 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/54012/ints4-(integrator-complex-subunit-4)