Identity
HGNC
LOCATION
8p12
LOCUSID
ALIAS
FOAP-7,HSPC035,TMEM66,XTP3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51669
MIM: 614768
HGNC: 28789
Ensembl: ENSG00000133872
Variants:
dbSNP: 51669
ClinVar: 51669
TCGA: ENSG00000133872
COSMIC: SARAF
RNA/Proteins
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38073055 | 2024 | Reduced Ca(2+) mobilization in neonatal human platelets involves SARAF and pannexin-1. | 0 |
| 38802035 | 2024 | MiR-30a-5p isoform -1|1 promotes the progression of gastric cancer by inhibiting TMEM66 and reducing intratumoral cytotoxic T cells. | 0 |
| 38073055 | 2024 | Reduced Ca(2+) mobilization in neonatal human platelets involves SARAF and pannexin-1. | 0 |
| 38802035 | 2024 | MiR-30a-5p isoform -1|1 promotes the progression of gastric cancer by inhibiting TMEM66 and reducing intratumoral cytotoxic T cells. | 0 |
| 34705029 | 2021 | Bidirectional regulation of calcium release-activated calcium (CRAC) channel by SARAF. | 7 |
| 34705029 | 2021 | Bidirectional regulation of calcium release-activated calcium (CRAC) channel by SARAF. | 7 |
| 32079527 | 2020 | Chemoresistant ovarian cancer enhances its migration abilities by increasing store-operated Ca(2+) entry-mediated turnover of focal adhesions. | 21 |
| 32394484 | 2020 | Temporal modulation of calcium sensing in hematopoietic stem cells is crucial for proper stem cell expansion and engraftment. | 10 |
| 32079527 | 2020 | Chemoresistant ovarian cancer enhances its migration abilities by increasing store-operated Ca(2+) entry-mediated turnover of focal adhesions. | 21 |
| 32394484 | 2020 | Temporal modulation of calcium sensing in hematopoietic stem cells is crucial for proper stem cell expansion and engraftment. | 10 |
| 30975919 | 2019 | STIM1 phosphorylation at Y(316) modulates its interaction with SARAF and the activation of SOCE and I(CRAC). | 23 |
| 31082439 | 2019 | SARAF Luminal Domain Structure Reveals a Novel Domain-Swapped β-Sandwich Fold Important for SOCE Modulation. | 9 |
| 31493399 | 2019 | Ca(2+) Influx Channel Inhibitor SARAF Protects Mice From Acute Pancreatitis. | 19 |
| 30975919 | 2019 | STIM1 phosphorylation at Y(316) modulates its interaction with SARAF and the activation of SOCE and I(CRAC). | 23 |
| 31082439 | 2019 | SARAF Luminal Domain Structure Reveals a Novel Domain-Swapped β-Sandwich Fold Important for SOCE Modulation. | 9 |
Citation
Dessen P
SARAF (store-operated calcium entry associated regulatory factor)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/54028/saraf-(store-operated-calcium-entry-associated-regulatory-factor)
