DUX4L1 (double homeobox 4 like 1 (pseudogene))

2014-06-01  

Identity

HGNC
LOCATION
4q35.2
LOCUSID
ALIAS
DUX10,DUX4
FUSION GENES

Other Information

Locus ID:

NCBI: 22947
HGNC: 3082
Ensembl: ENSG00000280757

Variants:

dbSNP: 22947
ClinVar: 22947
TCGA: ENSG00000280757
COSMIC: DUX4L1

RNA/Proteins

References

Pubmed IDYearTitleCitations
336937052021Nanopore direct RNA sequencing detects DUX4-activated repeats and isoforms in human muscle cells.11
336937052021Nanopore direct RNA sequencing detects DUX4-activated repeats and isoforms in human muscle cells.11
245897352014Dux4 induces cell cycle arrest at G1 phase through upregulation of p21 expression.26
246369942014Myogenic enhancers regulate expression of the facioscapulohumeral muscular dystrophy-associated DUX4 gene.40
245897352014Dux4 induces cell cycle arrest at G1 phase through upregulation of p21 expression.26
246369942014Myogenic enhancers regulate expression of the facioscapulohumeral muscular dystrophy-associated DUX4 gene.40
231081592013Expression of DUX4 in zebrafish development recapitulates facioscapulohumeral muscular dystrophy.47
232062572013DUX4 expression in FSHD muscle cells: how could such a rare protein cause a myopathy?85
235606602013Expression of the human FSHD-linked DUX4 gene induces neurogenesis during differentiation of murine embryonic stem cells.9
236446002013Telomere position effect regulates DUX4 in human facioscapulohumeral muscular dystrophy.57
237176502013DUX4 differentially regulates transcriptomes of human rhabdomyosarcoma and mouse C2C12 cells.39
238216462013Wnt/β-catenin signaling suppresses DUX4 expression and prevents apoptosis of FSHD muscle cells.69
238871642013Undifferentiated small round cell sarcoma with t(4;19)(q35;q13.1) CIC-DUX4 fusion: a novel highly aggressive soft tissue tumor with distinctive histopathology.38
240309472013Large scale genotype-phenotype analyses indicate that novel prognostic tools are required for families with facioscapulohumeral muscular dystrophy.54
241160602013Multiple protein domains contribute to nuclear import and cell toxicity of DUX4, a candidate pathogenic protein for facioscapulohumeral muscular dystrophy.17

Citation

Dessen P

DUX4L1 (double homeobox 4 like 1 (pseudogene))

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/54029/dux4l1-(double-homeobox-4-like-1-(pseudogene))