Identity
HGNC
LOCATION
13q12.3
LOCUSID
ALIAS
ATRC1,CAT-1,ERR,HCAT1,REC1L
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6541
MIM: 104615
HGNC: 11057
Ensembl: ENSG00000139514
Variants:
dbSNP: 6541
ClinVar: 6541
TCGA: ENSG00000139514
COSMIC: SLC7A1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000139514 | ENST00000380752 | P30825 |
| ENSG00000139514 | ENST00000380752 | A0A024RDQ9 |
| ENSG00000139514 | ENST00000450494 | Q5JR49 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38547677 | 2024 | The solute carrier SLC7A1 may act as a protein transporter at the blood-brain barrier. | 1 |
| 38752472 | 2024 | High expression of SLC7A1 in high-grade serous ovarian cancer promotes tumor progression and is involved in MAPK/ERK pathway and EMT. | 0 |
| 38547677 | 2024 | The solute carrier SLC7A1 may act as a protein transporter at the blood-brain barrier. | 1 |
| 38752472 | 2024 | High expression of SLC7A1 in high-grade serous ovarian cancer promotes tumor progression and is involved in MAPK/ERK pathway and EMT. | 0 |
| 34314821 | 2021 | High total cholesterol and triglycerides levels increase arginases metabolism, impairing nitric oxide signaling and worsening fetoplacental endothelial dysfunction in gestational diabetes mellitus pregnancies. | 3 |
| 34314821 | 2021 | High total cholesterol and triglycerides levels increase arginases metabolism, impairing nitric oxide signaling and worsening fetoplacental endothelial dysfunction in gestational diabetes mellitus pregnancies. | 3 |
| 32008093 | 2020 | Human cationic amino acid transporters are not affected by direct nitros(yl)ation. | 1 |
| 32008093 | 2020 | Human cationic amino acid transporters are not affected by direct nitros(yl)ation. | 1 |
| 28684763 | 2017 | The prognostic biomarker L-homoarginine is a substrate of the cationic amino acid transporters CAT1, CAT2A and CAT2B. | 19 |
| 28684763 | 2017 | The prognostic biomarker L-homoarginine is a substrate of the cationic amino acid transporters CAT1, CAT2A and CAT2B. | 19 |
| 26062636 | 2015 | Estradiol augments while progesterone inhibits arginine transport in human endothelial cells through modulation of cationic amino acid transporter-1. | 8 |
| 26062636 | 2015 | Estradiol augments while progesterone inhibits arginine transport in human endothelial cells through modulation of cationic amino acid transporter-1. | 8 |
| 22870827 | 2013 | Differential topochemistry of three cationic amino acid transporter proteins, hCAT1, hCAT2 and hCAT3, in the adult human brain. | 3 |
| 23009292 | 2013 | Nitric oxide signalling pathway in Duchenne muscular dystrophy mice: up-regulation of L-arginine transporters. | 25 |
| 23841815 | 2013 | Contribution of SLC7A1 genetic variant to hypertension, the TAMRISK study. | 3 |
Citation
Dessen P
SLC7A1 (solute carrier family 7 member 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-06-01
Online version: http://atlasgeneticsoncology.org/gene/54032/meetings/
