MTERF1 (mitochondrial transcription termination factor 1)

2014-06-01  

Identity

HGNC
LOCATION
7q21.2
LOCUSID
ALIAS
MTERF
FUSION GENES

Other Information

Locus ID:

NCBI: 7978
MIM: 602318
HGNC: 21463
Ensembl: ENSG00000127989

Variants:

dbSNP: 7978
ClinVar: 7978
TCGA: ENSG00000127989
COSMIC: MTERF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000127989ENST00000351870Q99551
ENSG00000127989ENST00000406735B4DPR9
ENSG00000127989ENST00000419292B4DPR9
ENSG00000127989ENST00000425936C9JU79
ENSG00000127989ENST00000442961C9JE25
ENSG00000127989ENST00000456229C9JNM8

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial biogenesisREACTOMER-HSA-1592230
Transcriptional activation of mitochondrial biogenesisREACTOMER-HSA-2151201
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionREACTOMER-HSA-504046
Transcription from mitochondrial promotersREACTOMER-HSA-75944
Mitochondrial transcription terminationREACTOMER-HSA-163316

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
384884922024FAK mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation by modulating mitochondrial transcription termination factor 1/cyclin D1.0
384884922024FAK mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation by modulating mitochondrial transcription termination factor 1/cyclin D1.0
265236812016Base Flipping by MTERF1 Can Accommodate Multiple Conformations and Occurs in a Stepwise Fashion.0
271125702016Mitochondrial transcription termination factor 1 directs polar replication fork pausing.20
265236812016Base Flipping by MTERF1 Can Accommodate Multiple Conformations and Occurs in a Stepwise Fashion.0
271125702016Mitochondrial transcription termination factor 1 directs polar replication fork pausing.20
213269082011Mitochondrial transcription: how does it end?8
214477782011Inherited variants in mitochondrial biogenesis genes may influence epithelial ovarian cancer risk.44
214506912011hMTERF4 knockdown in HeLa cells results in sub-G1 cell accumulation and cell death.2
213269082011Mitochondrial transcription: how does it end?8
214477782011Inherited variants in mitochondrial biogenesis genes may influence epithelial ovarian cancer risk.44
214506912011hMTERF4 knockdown in HeLa cells results in sub-G1 cell accumulation and cell death.2
196817682010Training response of mitochondrial transcription factors in human skeletal muscle.14
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
205438262010Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat.25

Citation

Dessen P

MTERF1 (mitochondrial transcription termination factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/54038/mterf1-(mitochondrial-transcription-termination-factor-1)