CMTM7 (CKLF like MARVEL transmembrane domain containing 7)

2014-07-01  

Identity

HGNC
CMTM7
LOCATION
3p22.3
LOCUSID
112616
ALIAS
CKLFSF7
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 112616
MIM: 607890
HGNC: 19178
Ensembl: ENSG00000153551

Variants:

dbSNP: 112616
ClinVar: 112616
TCGA: ENSG00000153551
COSMIC: CMTM7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153551ENST00000334983Q96FZ5
ENSG00000153551ENST00000334983A0A024R2L3
ENSG00000153551ENST00000349718Q96FZ5
ENSG00000153551ENST00000454304F8WDZ3
ENSG00000153551ENST00000465248H0YFU6
ENSG00000153551ENST00000487007H0YGW1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
127821302003Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation.31
204007782010Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium.28
238932432014A novel 3p22.3 gene CMTM7 represses oncogenic EGFR signaling and inhibits cancer cell growth.16
265286972015CMTM7 knockdown increases tumorigenicity of human non-small cell lung cancer cells and EGFR-AKT signaling by reducing Rab5 activation.9
223637432012Identification of CMTM7 as a transmembrane linker of BLNK and the B-cell receptor.7
239816022013Change of CMTM7 expression, a potential tumor suppressor, is associated with poor clinical outcome in human non-small cell lung cancer.4
309036812019Overexpression of CMTM7 inhibits cell growth and migration in liver cancer.2
303929142018SOX10-dependent CMTM7 expression inhibits cell proliferation and tumor growth in gastric carcinoma.0

Citation

Dessen P

CMTM7 (CKLF like MARVEL transmembrane domain containing 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-07-01

Online version: http://atlasgeneticsoncology.org/gene/54052/cmtm7-(cklf-like-marvel-transmembrane-domain-containing-7)