Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9355
MIM: 603759
HGNC: 6594
Ensembl: ENSG00000106689
Variants:
dbSNP: 9355
ClinVar: 9355
TCGA: ENSG00000106689
COSMIC: LHX2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000106689 | ENST00000373615 | P50458 |
| ENSG00000106689 | ENST00000446480 | H7C0H1 |
| ENSG00000106689 | ENST00000488674 | U3KQT5 |
| ENSG00000106689 | ENST00000560961 | H0YM35 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36649236 | 2023 | The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration. | 1 |
| 37057675 | 2023 | LHX2 haploinsufficiency causes a variable neurodevelopmental disorder. | 2 |
| 37518356 | 2023 | LIM Homeobox 2 Increases Adhesion-Regulating Molecule 1 Transcription to Facilitate the Pathological Progression of Oxidized Low-Density Lipoprotein-Stimulated Atherosclerotic Cell Models. | 0 |
| 36649236 | 2023 | The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration. | 1 |
| 37057675 | 2023 | LHX2 haploinsufficiency causes a variable neurodevelopmental disorder. | 2 |
| 37518356 | 2023 | LIM Homeobox 2 Increases Adhesion-Regulating Molecule 1 Transcription to Facilitate the Pathological Progression of Oxidized Low-Density Lipoprotein-Stimulated Atherosclerotic Cell Models. | 0 |
| 35864158 | 2022 | LHX2 facilitates the progression of nasopharyngeal carcinoma via activation of the FGF1/FGFR axis. | 2 |
| 35864158 | 2022 | LHX2 facilitates the progression of nasopharyngeal carcinoma via activation of the FGF1/FGFR axis. | 2 |
| 33933312 | 2021 | REGγ regulates hair cycle by activating Lgr5 positive hair follicle stem cells. | 2 |
| 33933312 | 2021 | REGγ regulates hair cycle by activating Lgr5 positive hair follicle stem cells. | 2 |
| 30765795 | 2019 | LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells. | 10 |
| 31724536 | 2019 | LHX2 promotes malignancy and inhibits autophagy via mTOR in osteosarcoma and is negatively regulated by miR-129-5p. | 14 |
| 30765795 | 2019 | LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells. | 10 |
| 31724536 | 2019 | LHX2 promotes malignancy and inhibits autophagy via mTOR in osteosarcoma and is negatively regulated by miR-129-5p. | 14 |
| 29278703 | 2018 | Overexpression of Lhx2 suppresses proliferation of human T cell acute lymphoblastic leukemia-derived cells, partly by reducing LMO2 protein levels. | 3 |
Citation
Dessen P
LHX2 (LIM homeobox 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-07-01
Online version: http://atlasgeneticsoncology.org/gene/54067/lhx2-(lim-homeobox-2)
