CMTM3 (CKLF like MARVEL transmembrane domain containing 3)

2014-07-01  

Identity

HGNC
LOCATION
16q22.1
LOCUSID
ALIAS
BNAS2,CKLFSF3
FUSION GENES

Other Information

Locus ID:

NCBI: 123920
MIM: 607886
HGNC: 19174
Ensembl: ENSG00000140931

Variants:

dbSNP: 123920
ClinVar: 123920
TCGA: ENSG00000140931
COSMIC: CMTM3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140931ENST00000361909Q96MX0
ENSG00000140931ENST00000361909A0A024R6Y8
ENSG00000140931ENST00000424011Q96MX0
ENSG00000140931ENST00000424011A0A024R6Y8
ENSG00000140931ENST00000460097B3KQJ8
ENSG00000140931ENST00000562357H3BN06
ENSG00000140931ENST00000562707Q96MX0
ENSG00000140931ENST00000562707A0A024R6Y8
ENSG00000140931ENST00000563672H3BU39
ENSG00000140931ENST00000564060H3BUD5
ENSG00000140931ENST00000565003I3L3C2
ENSG00000140931ENST00000565666J3KSM1
ENSG00000140931ENST00000565922Q96MX0
ENSG00000140931ENST00000566121B3KQJ8
ENSG00000140931ENST00000566756J3KSR6
ENSG00000140931ENST00000567572Q96MX0
ENSG00000140931ENST00000567572A0A024R6Y8
ENSG00000140931ENST00000568477B3KQJ8

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
340480992021Familial hypereosinophilia associated with eosinophilic gastrointestinal symptoms in individuals with a missense mutation in CKLF-like MARVEL transmembrane domain containing 3.0
340480992021Familial hypereosinophilia associated with eosinophilic gastrointestinal symptoms in individuals with a missense mutation in CKLF-like MARVEL transmembrane domain containing 3.0
293452972018miR-135b-5p promotes gastric cancer progression by targeting CMTM3.28
293452972018miR-135b-5p promotes gastric cancer progression by targeting CMTM3.28
276295432017CKLF-Like MARVEL Transmembrane Domain-Containing Member 3 (CMTM3) Inhibits the Proliferation and Tumorigenisis in Hepatocellular Carcinoma Cells.14
278670152017CMTM3 decreases EGFR expression and EGF-mediated tumorigenicity by promoting Rab5 activity in gastric cancer.35
284282202017CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions.22
287825762017DNA methylation of CMTM3, SSTR2, and MDFI genes in colorectal cancer.29
276295432017CKLF-Like MARVEL Transmembrane Domain-Containing Member 3 (CMTM3) Inhibits the Proliferation and Tumorigenisis in Hepatocellular Carcinoma Cells.14
278670152017CMTM3 decreases EGFR expression and EGF-mediated tumorigenicity by promoting Rab5 activity in gastric cancer.35
284282202017CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions.22
287825762017DNA methylation of CMTM3, SSTR2, and MDFI genes in colorectal cancer.29
271210552016Knockdown of CMTM3 promotes metastasis of gastric cancer via the STAT3/Twist1/EMT signaling pathway.28
271259752016CMTM3 presents a secreted form released via exosomes.4
275219942016Elevated methylation of CMTM3 promoter in the male laryngeal squamous cell carcinoma patients.16

Citation

Dessen P

CMTM3 (CKLF like MARVEL transmembrane domain containing 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-07-01

Online version: http://atlasgeneticsoncology.org/gene/54080/cmtm3-(cklf-like-marvel-transmembrane-domain-containing-3)