MIR718 (microRNA 718)

2014-07-01 Affiliation

Identity

HGNC

MIR718

LOCATION

Xq28

LOCUSID

100313781

ALIAS

hsa-mir-718

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 100313781
MIM: 300929
HGNC: 37317
Ensembl: ENSG00000284286
miRBase:

Variants:

dbSNP: 100313781
ClinVar: 100313781
TCGA: ENSG00000284286
COSMIC: MIR718

RNA/Proteins

Pathways

Pathway	Source	External ID
Immune System	REACTOME	R-HSA-168256
Innate Immune System	REACTOME	R-HSA-168249
Toll-Like Receptors Cascades	REACTOME	R-HSA-168898
Toll Like Receptor 10 (TLR10) Cascade	REACTOME	R-HSA-168142
MyD88 cascade initiated on plasma membrane	REACTOME	R-HSA-975871
IRAK1 recruits IKK complex	REACTOME	R-HSA-937039
TAK1 activates NFkB by phosphorylation and activation of IKKs complex	REACTOME	R-HSA-445989
MAP kinase activation in TLR cascade	REACTOME	R-HSA-450294
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	REACTOME	R-HSA-450321
activated TAK1 mediates p38 MAPK activation	REACTOME	R-HSA-450302
Toll Like Receptor 3 (TLR3) Cascade	REACTOME	R-HSA-168164
MyD88-independent TLR3/TLR4 cascade	REACTOME	R-HSA-166166
TRIF-mediated TLR3/TLR4 signaling	REACTOME	R-HSA-937061
Toll Like Receptor 5 (TLR5) Cascade	REACTOME	R-HSA-168176
Toll Like Receptor 7/8 (TLR7/8) Cascade	REACTOME	R-HSA-168181
MyD88 dependent cascade initiated on endosome	REACTOME	R-HSA-975155
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	REACTOME	R-HSA-975138
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	REACTOME	R-HSA-975144
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling	REACTOME	R-HSA-975110
Toll Like Receptor 9 (TLR9) Cascade	REACTOME	R-HSA-168138
Toll Like Receptor 4 (TLR4) Cascade	REACTOME	R-HSA-166016
Activated TLR4 signalling	REACTOME	R-HSA-166054
MyD88:Mal cascade initiated on plasma membrane	REACTOME	R-HSA-166058
Toll Like Receptor 2 (TLR2) Cascade	REACTOME	R-HSA-181438
Toll Like Receptor TLR1:TLR2 Cascade	REACTOME	R-HSA-168179
Toll Like Receptor TLR6:TLR2 Cascade	REACTOME	R-HSA-168188
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	REACTOME	R-HSA-168643
NOD1/2 Signaling Pathway	REACTOME	R-HSA-168638
Cytokine Signaling in Immune system	REACTOME	R-HSA-1280215
Signaling by Interleukins	REACTOME	R-HSA-449147
Interleukin-1 signaling	REACTOME	R-HSA-446652
Signal Transduction	REACTOME	R-HSA-162582
Signalling by NGF	REACTOME	R-HSA-166520
p75 NTR receptor-mediated signalling	REACTOME	R-HSA-193704
p75NTR signals via NF-kB	REACTOME	R-HSA-193639
p75NTR recruits signalling complexes	REACTOME	R-HSA-209543
NF-kB is activated and signals survival	REACTOME	R-HSA-209560

References

Pubmed ID	Year	Title	Citations
31251699	2019	MiR-718 mediates the indirect interaction between lncRNA SEMA3B-AS1 and PTEN to regulate the proliferation of hepatocellular carcinoma cells.	15
31251699	2019	MiR-718 mediates the indirect interaction between lncRNA SEMA3B-AS1 and PTEN to regulate the proliferation of hepatocellular carcinoma cells.	15
30131483	2018	High miR-718 Suppresses Phosphatase and Tensin Homolog (PTEN) Expression and Correlates to Unfavorable Prognosis in Gastric Cancer.	10
30166214	2018	miR-718 is involved in malignancy of papillary thyroid cancer through repression of PDPK1.	12
30131483	2018	High miR-718 Suppresses Phosphatase and Tensin Homolog (PTEN) Expression and Correlates to Unfavorable Prognosis in Gastric Cancer.	10
30166214	2018	miR-718 is involved in malignancy of papillary thyroid cancer through repression of PDPK1.	12
28070994	2017	Involvement of microRNA-718, a new regulator of EGR3, in regulation of malignant phenotype of HCC cells.	14
28070994	2017	Involvement of microRNA-718, a new regulator of EGR3, in regulation of malignant phenotype of HCC cells.	14
26756617	2016	Predictive value of plasma miRNA-718 for esophageal squamous cell carcinoma.	12
26756617	2016	Predictive value of plasma miRNA-718 for esophageal squamous cell carcinoma.	12
25584485	2015	Identification of a bona fide microRNA biomarker in serum exosomes that predicts hepatocellular carcinoma recurrence after liver transplantation.	162
25584485	2015	Identification of a bona fide microRNA biomarker in serum exosomes that predicts hepatocellular carcinoma recurrence after liver transplantation.	162
24815691	2014	MiR-718 represses VEGF and inhibits ovarian cancer cell progression.	18
24815691	2014	MiR-718 represses VEGF and inhibits ovarian cancer cell progression.	18

Citation

Dessen P

MIR718 (microRNA 718)

Atlas Genet Cytogenet Oncol Haematol. 2014-07-01

Online version: http://atlasgeneticsoncology.org/gene/54082/mir718-(microrna-718)

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