Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10299
MIM: 613297
HGNC: 30550
Ensembl: ENSG00000145495
Variants:
dbSNP: 10299
ClinVar: 10299
TCGA: ENSG00000145495
COSMIC: MARCHF6
RNA/Proteins
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33049405 | 2021 | The E3 ubiquitin ligase MARCHF6 as a metabolic integrator in cholesterol synthesis and beyond. | 9 |
| 34273954 | 2021 | MARCH6 promotes hepatocellular carcinoma development through up-regulation of ATF2. | 4 |
| 34512155 | 2021 | MARCH6 promotes Papillary Thyroid Cancer development by destabilizing DHX9. | 9 |
| 33049405 | 2021 | The E3 ubiquitin ligase MARCHF6 as a metabolic integrator in cholesterol synthesis and beyond. | 9 |
| 34273954 | 2021 | MARCH6 promotes hepatocellular carcinoma development through up-regulation of ATF2. | 4 |
| 34512155 | 2021 | MARCH6 promotes Papillary Thyroid Cancer development by destabilizing DHX9. | 9 |
| 31904814 | 2020 | The cholesterol synthesis enzyme lanosterol 14α-demethylase is post-translationally regulated by the E3 ubiquitin ligase MARCH6. | 11 |
| 32755570 | 2020 | The MARCH6-SQLE Axis Controls Endothelial Cholesterol Homeostasis and Angiogenic Sprouting. | 12 |
| 31904814 | 2020 | The cholesterol synthesis enzyme lanosterol 14α-demethylase is post-translationally regulated by the E3 ubiquitin ligase MARCH6. | 11 |
| 32755570 | 2020 | The MARCH6-SQLE Axis Controls Endothelial Cholesterol Homeostasis and Angiogenic Sprouting. | 12 |
| 30545937 | 2019 | Cholesterol increases protein levels of the E3 ligase MARCH6 and thereby stimulates protein degradation. | 14 |
| 30658189 | 2019 | Differential use of E2 ubiquitin conjugating enzymes for regulated degradation of the rate-limiting enzymes HMGCR and SQLE in cholesterol biosynthesis. | 9 |
| 31422115 | 2019 | Consulting prostate cancer cohort data uncovers transcriptional control: Regulation of the MARCH6 gene. | 6 |
| 31664039 | 2019 | Unstable TTTTA/TTTCA expansions in MARCH6 are associated with Familial Adult Myoclonic Epilepsy type 3. | 62 |
| 30545937 | 2019 | Cholesterol increases protein levels of the E3 ligase MARCH6 and thereby stimulates protein degradation. | 14 |
Citation
Dessen P
MARCHF6 (membrane associated ring-CH-type finger 6)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54088/marchf6-(membrane-associated-ring-ch-type-finger-6)
