ACAD11 (acyl-CoA dehydrogenase family member 11)

2014-08-01  

Identity

HGNC
ACAD11
LOCATION
3q22.1
LOCUSID
84129
ALIAS
ACAD-11
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84129
MIM: 614288
HGNC: 30211
Ensembl: ENSG00000240303

Variants:

dbSNP: 84129
ClinVar: 84129
TCGA: ENSG00000240303
COSMIC: ACAD11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000240303ENST00000264990Q709F0
ENSG00000240303ENST00000481970D6RDI8
ENSG00000240303ENST00000485198F8WEV0
ENSG00000240303ENST00000510100H0Y9C6

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Mitochondrial Fatty Acid Beta-OxidationREACTOMER-HSA-77289

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
212376832011Identification and characterization of new long chain acyl-CoA dehydrogenases.20
194235402009Common variation in genes related to innate immunity and risk of adult glioma.19
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
257048132015Analysis of p53 transactivation domain mutants reveals Acad11 as a metabolic target important for p53 pro-survival function.16
204069642010Risk of meningioma and common variation in genes related to innate immunity.12
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.5

Citation

Dessen P

ACAD11 (acyl-CoA dehydrogenase family member 11)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54100/acad11-(acyl-coa-dehydrogenase-family-member-11)