Identity
HGNC
LOCATION
14q24.3
LOCUSID
ALIAS
MMSADHA,MMSDH
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4329
MIM: 603178
HGNC: 7179
Ensembl: ENSG00000119711
Variants:
dbSNP: 4329
ClinVar: 4329
TCGA: ENSG00000119711
COSMIC: ALDH6A1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000119711 | ENST00000350259 | Q02252 |
| ENSG00000119711 | ENST00000553458 | Q02252 |
| ENSG00000119711 | ENST00000553458 | A0A024R6G4 |
| ENSG00000119711 | ENST00000555126 | G3V4Z4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35907565 | 2022 | ALDH6A1 weakens the progression of colon cancer via modulating the RAS/RAF/MEK/ERK pathway in cancer cell lines. | 2 |
| 36098688 | 2022 | The downregulated drug-metabolism related ALDH6A1 serves as predictor for prognosis and therapeutic immune response in gastric cancer. | 3 |
| 35907565 | 2022 | ALDH6A1 weakens the progression of colon cancer via modulating the RAS/RAF/MEK/ERK pathway in cancer cell lines. | 2 |
| 36098688 | 2022 | The downregulated drug-metabolism related ALDH6A1 serves as predictor for prognosis and therapeutic immune response in gastric cancer. | 3 |
| 33686951 | 2021 | Identification and validation of a two-gene metabolic signature for survival prediction in patients with kidney renal clear cell carcinoma. | 6 |
| 33686951 | 2021 | Identification and validation of a two-gene metabolic signature for survival prediction in patients with kidney renal clear cell carcinoma. | 6 |
| 31985234 | 2020 | Identification of ALDH6A1 as a Potential Molecular Signature in Hepatocellular Carcinoma via Quantitative Profiling of the Mitochondrial Proteome. | 15 |
| 31985234 | 2020 | Identification of ALDH6A1 as a Potential Molecular Signature in Hepatocellular Carcinoma via Quantitative Profiling of the Mitochondrial Proteome. | 15 |
| 30396985 | 2018 | HSP27, ALDH6A1 and Prohibitin Act as a Trio-biomarker to Predict Survival in Late Metastatic Prostate Cancer. | 18 |
| 30396985 | 2018 | HSP27, ALDH6A1 and Prohibitin Act as a Trio-biomarker to Predict Survival in Late Metastatic Prostate Cancer. | 18 |
| 25099943 | 2014 | Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss. | 18 |
| 25099943 | 2014 | Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss. | 18 |
| 21863277 | 2012 | 3-Hydroxyisobutyrate aciduria and mutations in the ALDH6A1 gene coding for methylmalonate semialdehyde dehydrogenase. | 18 |
| 21863277 | 2012 | 3-Hydroxyisobutyrate aciduria and mutations in the ALDH6A1 gene coding for methylmalonate semialdehyde dehydrogenase. | 18 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
Citation
Dessen P
ALDH6A1 (aldehyde dehydrogenase 6 family member A1)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54114/aldh6a1-(aldehyde-dehydrogenase-6-family-member-a1)
