Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 257
MIM: 606014
HGNC: 449
Ensembl: ENSG00000156150
Variants:
dbSNP: 257
ClinVar: 257
TCGA: ENSG00000156150
COSMIC: ALX3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000156150 | ENST00000647563 | O95076 |
| ENSG00000156150 | ENST00000649954 | A0A3B3IS30 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34266408 | 2021 | Oncogenic role of ALX3 in cervical cancer cells through KDM2B-mediated histone demethylation of CDC25A. | 1 |
| 34266408 | 2021 | Oncogenic role of ALX3 in cervical cancer cells through KDM2B-mediated histone demethylation of CDC25A. | 1 |
| 29215096 | 2018 | Exome sequencing revealed a novel nonsense variant in ALX3 gene underlying frontorhiny. | 2 |
| 29215096 | 2018 | Exome sequencing revealed a novel nonsense variant in ALX3 gene underlying frontorhiny. | 2 |
| 22496059 | 2012 | Exclusion of mutations in TGIF, ALX3, and ALX4 genes in patients with the syndrome of frontonasal dysgenesis, callosal agenesis, basal encephalocele, and eye anomalies. | 0 |
| 22496059 | 2012 | Exclusion of mutations in TGIF, ALX3, and ALX4 genes in patients with the syndrome of frontonasal dysgenesis, callosal agenesis, basal encephalocele, and eye anomalies. | 0 |
| 22106187 | 2011 | Clinical and genetic characterization of frontorhiny: report of 3 novel cases and discussion of the surgical management. | 2 |
| 22106187 | 2011 | Clinical and genetic characterization of frontorhiny: report of 3 novel cases and discussion of the surgical management. | 2 |
| 20634891 | 2010 | Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. | 28 |
| 20634891 | 2010 | Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. | 28 |
| 19409524 | 2009 | Frontorhiny, a distinctive presentation of frontonasal dysplasia caused by recessive mutations in the ALX3 homeobox gene. | 52 |
| 19409524 | 2009 | Frontorhiny, a distinctive presentation of frontonasal dysplasia caused by recessive mutations in the ALX3 homeobox gene. | 52 |
| 16825292 | 2006 | The homeoprotein Alx3 expressed in pancreatic beta-cells regulates insulin gene transcription by interacting with the basic helix-loop-helix protein E47. | 6 |
| 16825292 | 2006 | The homeoprotein Alx3 expressed in pancreatic beta-cells regulates insulin gene transcription by interacting with the basic helix-loop-helix protein E47. | 6 |
| 16825292 | 2006 | The homeoprotein Alx3 expressed in pancreatic beta-cells regulates insulin gene transcription by interacting with the basic helix-loop-helix protein E47. | 6 |
Citation
Dessen P
ALX3 (ALX homeobox 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54120/alx3-(alx-homeobox-3)
