Identity
HGNC
LOCATION
19q13.11
LOCUSID
ALIAS
PP12899,VARP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84079
HGNC: 25310
Ensembl: ENSG00000105186
Variants:
dbSNP: 84079
ClinVar: 84079
TCGA: ENSG00000105186
COSMIC: ANKRD27
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Vesicle-mediated transport | REACTOME | R-HSA-5653656 |
| Membrane Trafficking | REACTOME | R-HSA-199991 |
| RAB GEFs exchange GTP for GDP on RABs | REACTOME | R-HSA-8876198 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33024112 | 2020 | Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29. | 12 |
| 33024112 | 2020 | Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29. | 12 |
| 27103185 | 2016 | Multiple Roles of VARP in Endosomal Trafficking: Rabs, Retromer Components and R-SNARE VAMP7 Meet on VARP. | 17 |
| 27103185 | 2016 | Multiple Roles of VARP in Endosomal Trafficking: Rabs, Retromer Components and R-SNARE VAMP7 Meet on VARP. | 17 |
| 25407941 | 2014 | GWAS identifies four novel eosinophilic esophagitis loci. | 114 |
| 25407941 | 2014 | GWAS identifies four novel eosinophilic esophagitis loci. | 114 |
| 23104059 | 2012 | The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation. | 36 |
| 23104059 | 2012 | The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation. | 36 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19745841 | 2009 | Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth. | 47 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
| 19745841 | 2009 | Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth. | 47 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
| 18477474 | 2008 | Varp interacts with Rab38 and functions as its potential effector. | 16 |
Citation
Dessen P
ANKRD27 (ankyrin repeat domain 27)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54125/ankrd27-(ankyrin-repeat-domain-27)
