Identity
HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
C12orf3,TMEM16B
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57101
MIM: 610109
HGNC: 1183
Ensembl: ENSG00000047617
Variants:
dbSNP: 57101
ClinVar: 57101
TCGA: ENSG00000047617
COSMIC: ANO2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10066 | duloxetine | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | 29407288 | |
| PA447321 | Depressive Disorder, Major | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | 29407288 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33651839 | 2021 | Anoctamin 2-chloride channels reduce simple spike activity and mediate inhibition at elevated calcium concentration in cerebellar Purkinje cells. | 4 |
| 33651839 | 2021 | Anoctamin 2-chloride channels reduce simple spike activity and mediate inhibition at elevated calcium concentration in cerebellar Purkinje cells. | 4 |
| 31375628 | 2019 | Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk. | 78 |
| 31375628 | 2019 | Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk. | 78 |
| 28046119 | 2017 | Permeation Mechanisms in the TMEM16B Calcium-Activated Chloride Channels. | 6 |
| 28046119 | 2017 | Permeation Mechanisms in the TMEM16B Calcium-Activated Chloride Channels. | 6 |
| 26862169 | 2016 | Anoctamin 2 identified as an autoimmune target in multiple sclerosis. | 52 |
| 26862169 | 2016 | Anoctamin 2 identified as an autoimmune target in multiple sclerosis. | 52 |
| 25635880 | 2015 | Assessment of the olfactory function in Italian patients with type 3 von Willebrand disease caused by a homozygous 253 Kb deletion involving VWF and TMEM16B/ANO2. | 2 |
| 25635880 | 2015 | Assessment of the olfactory function in Italian patients with type 3 von Willebrand disease caused by a homozygous 253 Kb deletion involving VWF and TMEM16B/ANO2. | 2 |
| 24928056 | 2014 | Calcium-activated chloride channels anoctamin 1 and 2 promote murine uterine smooth muscle contractility. | 21 |
| 25489088 | 2014 | Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl- channels. | 23 |
| 24928056 | 2014 | Calcium-activated chloride channels anoctamin 1 and 2 promote murine uterine smooth muscle contractility. | 21 |
| 25489088 | 2014 | Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl- channels. | 23 |
| 23570556 | 2013 | TMEM16A-TMEM16B chimaeras to investigate the structure-function relationship of calcium-activated chloride channels. | 22 |
Citation
Dessen P
ANO2 (anoctamin 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54128/chromosome-explorer/tumors-explorer/
