Identity
HGNC
LOCATION
11p15.5
LOCUSID
ALIAS
ADTAB,CLAPA2,HIP-9,HIP9,HYPJ
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 161
MIM: 607242
HGNC: 562
Ensembl: ENSG00000183020
Variants:
dbSNP: 161
ClinVar: 161
TCGA: ENSG00000183020
COSMIC: AP2A2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38772452 | 2024 | AP2A2 mutation and defective endocytosis in a Malian family with hereditary spastic paraplegia. | 0 |
| 38772452 | 2024 | AP2A2 mutation and defective endocytosis in a Malian family with hereditary spastic paraplegia. | 0 |
| 31748784 | 2020 | Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene. | 15 |
| 31748784 | 2020 | Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene. | 15 |
| 30086706 | 2018 | A genetic variant near adaptor-related protein complex 2 alpha 2 subunit gene is associated with coronary artery disease in a Chinese population. | 3 |
| 30086706 | 2018 | A genetic variant near adaptor-related protein complex 2 alpha 2 subunit gene is associated with coronary artery disease in a Chinese population. | 3 |
| 28003333 | 2017 | Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2. | 88 |
| 28003333 | 2017 | Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2. | 88 |
| 22360420 | 2012 | Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. | 24 |
| 22360420 | 2012 | Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. | 24 |
| 19129443 | 2009 | A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex. | 37 |
| 19359243 | 2009 | HM1.24 is internalized from lipid rafts by clathrin-mediated endocytosis through interaction with alpha-adaptin. | 95 |
| 19129443 | 2009 | A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex. | 37 |
| 19359243 | 2009 | HM1.24 is internalized from lipid rafts by clathrin-mediated endocytosis through interaction with alpha-adaptin. | 95 |
| 14530274 | 2003 | The AP-2 complex is excluded from the dynamic population of plasma membrane-associated clathrin. | 29 |
Citation
Dessen P
AP2A2 (adaptor related protein complex 2 subunit alpha 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54130/ap2a2-(adaptor-related-protein-complex-2-subunit-alpha-2)
