Identity
HGNC
LOCATION
Xp22.11
LOCUSID
ALIAS
FAM121B,MIC26,MICOS26,Mic23,My025
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79135
MIM: 300753
HGNC: 28727
Ensembl: ENSG00000184831
Variants:
dbSNP: 79135
ClinVar: 79135
TCGA: ENSG00000184831
COSMIC: APOO
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37649161 | 2023 | A X-linked nonsense APOO/MIC26 variant causes a lethal mitochondrial disease with progeria-like phenotypes. | 0 |
| 37649161 | 2023 | A X-linked nonsense APOO/MIC26 variant causes a lethal mitochondrial disease with progeria-like phenotypes. | 0 |
| 35588578 | 2022 | Role of apolipoprotein O in autophagy via the p38 mitogen-activated protein kinase signaling pathway in myocardial infarction. | 1 |
| 35588578 | 2022 | Role of apolipoprotein O in autophagy via the p38 mitogen-activated protein kinase signaling pathway in myocardial infarction. | 1 |
| 32439808 | 2021 | Mutation in the MICOS subunit gene APOO (MIC26) associated with an X-linked recessive mitochondrial myopathy, lactic acidosis, cognitive impairment and autistic features. | 19 |
| 32439808 | 2021 | Mutation in the MICOS subunit gene APOO (MIC26) associated with an X-linked recessive mitochondrial myopathy, lactic acidosis, cognitive impairment and autistic features. | 19 |
| 32788226 | 2020 | MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes. | 19 |
| 32788226 | 2020 | MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes. | 19 |
| 30092269 | 2018 | Loss of MICOS complex integrity and mitochondrial damage, but not TDP-43 mitochondrial localisation, are likely associated with severity of CHCHD10-related diseases. | 29 |
| 30092269 | 2018 | Loss of MICOS complex integrity and mitochondrial damage, but not TDP-43 mitochondrial localisation, are likely associated with severity of CHCHD10-related diseases. | 29 |
| 25764979 | 2015 | The non-glycosylated isoform of MIC26 is a constituent of the mammalian MICOS complex and promotes formation of crista junctions. | 32 |
| 25764979 | 2015 | The non-glycosylated isoform of MIC26 is a constituent of the mammalian MICOS complex and promotes formation of crista junctions. | 32 |
| 24743151 | 2014 | Apolipoprotein O is mitochondrial and promotes lipotoxicity in heart. | 26 |
| 24743151 | 2014 | Apolipoprotein O is mitochondrial and promotes lipotoxicity in heart. | 26 |
| 24341743 | 2013 | Microarray analysis provides new insights into the function of apolipoprotein O in HepG2 cell line. | 6 |
Citation
Dessen P
APOO (apolipoprotein O)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54131/apoo-(apolipoprotein-o)
