Identity
HGNC
LOCATION
10q11.23
LOCUSID
ALIAS
BCDase,HNAC1,LCDase,N-CDase,NCDase
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56624
MIM: 611202
HGNC: 18860
Ensembl: ENSG00000188611
Variants:
dbSNP: 56624
ClinVar: 56624
TCGA: ENSG00000188611
COSMIC: ASAH2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35134389 | 2022 | Measurement of neutral ceramidase activity in vitro and in vivo. | 1 |
| 35134389 | 2022 | Measurement of neutral ceramidase activity in vitro and in vivo. | 1 |
| 33547170 | 2021 | Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis. | 36 |
| 33547170 | 2021 | Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis. | 36 |
| 30389354 | 2019 | Neutral ceramidase: Advances in mechanisms, cell regulation, and roles in cancer. | 16 |
| 30389354 | 2019 | Neutral ceramidase: Advances in mechanisms, cell regulation, and roles in cancer. | 16 |
| 26190575 | 2015 | Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase. | 28 |
| 26190575 | 2015 | Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase. | 28 |
| 24397980 | 2014 | Adiponectin inhibits tumor necrosis factor-α-induced vascular inflammatory response via caveolin-mediated ceramidase recruitment and activation. | 42 |
| 24397980 | 2014 | Adiponectin inhibits tumor necrosis factor-α-induced vascular inflammatory response via caveolin-mediated ceramidase recruitment and activation. | 42 |
| 21530485 | 2011 | AP-1 binding transcriptionally regulates human neutral ceramidase. | 11 |
| 21531200 | 2011 | Transcriptional regulation of the human neutral ceramidase gene. | 3 |
| 21530485 | 2011 | AP-1 binding transcriptionally regulates human neutral ceramidase. | 11 |
| 21531200 | 2011 | Transcriptional regulation of the human neutral ceramidase gene. | 3 |
| 20520628 | 2010 | Hydrolytic pathway protects against ceramide-induced apoptosis in keratinocytes exposed to UVB. | 0 |
Citation
Dessen P
ASAH2 (N-acylsphingosine amidohydrolase 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54137/asah2-(n-acylsphingosine-amidohydrolase-2)
