Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56970
HGNC: 25416
Ensembl: ENSG00000087152
Variants:
dbSNP: 56970
ClinVar: 56970
TCGA: ENSG00000087152
COSMIC: ATXN7L3
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
| HATs acetylate histones | REACTOME | R-HSA-3214847 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35192684 | 2022 | Enhancer retargeting of CDX2 and UBTF::ATXN7L3 define a subtype of high-risk B-progenitor acute lymphoblastic leukemia. | 14 |
| 35316324 | 2022 | Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL. | 9 |
| 35192684 | 2022 | Enhancer retargeting of CDX2 and UBTF::ATXN7L3 define a subtype of high-risk B-progenitor acute lymphoblastic leukemia. | 14 |
| 35316324 | 2022 | Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL. | 9 |
| 31737900 | 2020 | Long non-coding RNA DSCAM-AS1 contributes to the tumorigenesis of cervical cancer by targeting miR-877-5p/ATXN7L3 axis. | 27 |
| 33186807 | 2020 | ATXN7L3 positively regulates SMAD7 transcription in hepatocellular carcinoma with growth inhibitory function. | 7 |
| 31737900 | 2020 | Long non-coding RNA DSCAM-AS1 contributes to the tumorigenesis of cervical cancer by targeting miR-877-5p/ATXN7L3 axis. | 27 |
| 33186807 | 2020 | ATXN7L3 positively regulates SMAD7 transcription in hepatocellular carcinoma with growth inhibitory function. | 7 |
| 27132940 | 2016 | ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth. | 72 |
| 27132940 | 2016 | ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth. | 72 |
| 21746879 | 2011 | The tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elements. | 80 |
| 21746879 | 2011 | The tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elements. | 80 |
| 20634802 | 2010 | The structural plasticity of SCA7 domains defines their differential nucleosome-binding properties. | 18 |
| 20634802 | 2010 | The structural plasticity of SCA7 domains defines their differential nucleosome-binding properties. | 18 |
| 18206972 | 2008 | A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing. | 198 |
Citation
Dessen P
ATXN7L3 (ataxin 7 like 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54146/atxn7l3-(ataxin-7-like-3)
