BICD1 (BICD cargo adaptor 1)

2014-08-01  

Identity

HGNC
BICD1
LOCATION
12p11.21
LOCUSID
636
ALIAS
BICD,bic-D
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 636
MIM: 602204
HGNC: 1049
Ensembl: ENSG00000151746

Variants:

dbSNP: 636
ClinVar: 636
TCGA: ENSG00000151746
COSMIC: BICD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000151746ENST00000395758A8MVZ6
ENSG00000151746ENST00000547680U3KQF7
ENSG00000151746ENST00000548411Q96G01
ENSG00000151746ENST00000550207F8VZX7
ENSG00000151746ENST00000551086F8W056
ENSG00000151746ENST00000551848Q96G01
ENSG00000151746ENST00000552160A0A087WYJ7
ENSG00000151746ENST00000652176Q96G01

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-independent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811436

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
372402442023Biallelic Loss-of-Function Variants in BICD1 Are Associated with Peripheral Neuropathy and Hearing Loss.0
372402442023Biallelic Loss-of-Function Variants in BICD1 Are Associated with Peripheral Neuropathy and Hearing Loss.0
318467912020A genome-wide by PM(10) interaction study identifies novel loci for lung function near BICD1 and IL1RN-IL1F10 genes in Korean adults.0
320880842020BICD1 functions as a prognostic biomarker and promotes hepatocellular carcinoma progression.4
318467912020A genome-wide by PM(10) interaction study identifies novel loci for lung function near BICD1 and IL1RN-IL1F10 genes in Korean adults.0
320880842020BICD1 functions as a prognostic biomarker and promotes hepatocellular carcinoma progression.4
304642252019BICD1 mediates HIF1α nuclear translocation in mesenchymal stem cells during hypoxia adaptation.19
315410152019FIGNL1 associates with KIF1Bβ and BICD1 to restrict dynein transport velocity during axon navigation.2
304642252019BICD1 mediates HIF1α nuclear translocation in mesenchymal stem cells during hypoxia adaptation.19
315410152019FIGNL1 associates with KIF1Bβ and BICD1 to restrict dynein transport velocity during axon navigation.2
282152932017Neuronal Roles of the Bicaudal D Family of Motor Adaptors.0
284103622017Joint Assessment of Donor and Recipient hTERT Gene Polymorphism Provides Additional Information for Early Kidney Transplantation Outcomes.3
282152932017Neuronal Roles of the Bicaudal D Family of Motor Adaptors.0
284103622017Joint Assessment of Donor and Recipient hTERT Gene Polymorphism Provides Additional Information for Early Kidney Transplantation Outcomes.3
274964262016BICD1 and Chromosome 18 Polymorphisms Associated With Recipients' Telomere Length Affect Kidney Allograft Function After Transplantation.2

Citation

Dessen P

BICD1 (BICD cargo adaptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54156/bicd1-(bicd-cargo-adaptor-1)