BIN2 (bridging integrator 2)

2014-08-01  

Identity

HGNC
LOCATION
12q13.13
LOCUSID
ALIAS
BRAP-1
FUSION GENES

Other Information

Locus ID:

NCBI: 51411
MIM: 605936
HGNC: 1053
Ensembl: ENSG00000110934

Variants:

dbSNP: 51411
ClinVar: 51411
TCGA: ENSG00000110934
COSMIC: BIN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000110934ENST00000452142Q9UBW5
ENSG00000110934ENST00000544402Q9UBW5
ENSG00000110934ENST00000604560S4R418
ENSG00000110934ENST00000605423S4R3J0
ENSG00000110934ENST00000615107Q9UBW5

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
109038462000Bin2, a functionally nonredundant member of the BAR adaptor gene family.14
232850272012Bin2 is a membrane sculpting N-BAR protein that influences leucocyte podosomes, motility and phagocytosis.13

Citation

Dessen P

BIN2 (bridging integrator 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54157/bin2-(bridging-integrator-2)